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A simulated annealing approach to define the genetic structure of populations
We present a new approach for defining groups of populations that are geographically homogeneous and maximally differentiated from each other. As a by‐product, it also leads to the identification ofExpand
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A new scenario for the quaternary history of European beech populations: palaeobotanical evidence and genetic consequences.
Here, palaeobotanical and genetic data for common beech (Fagus sylvatica) in Europe are used to evaluate the genetic consequences of long-term survival in refuge areas and postglacial spread. FourExpand
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Inferring admixture proportions from molecular data: extension to any number of parental populations.
The relative contribution of two parental populations to a hybrid group (the admixture proportions) can be estimated using not only the frequencies of different alleles, but also the degree ofExpand
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Distance from sub-Saharan Africa predicts mutational load in diverse human genomes
Significance Human genomes carry hundreds of mutations that are predicted to be deleterious in some environments, potentially affecting the health or fitness of an individual. We characterize theExpand
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Mitochondrial DNA diversity in South America and the genetic history of Andean highlanders.
We analyzed mtDNA sequence variation in 590 individuals from 18 south Amerindian populations. The spatial pattern of mtDNA diversity in these populations fits well the model proposed on the basis ofExpand
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On the accumulation of deleterious mutations during range expansions.
We investigate the effect of spatial range expansions on the evolution of fitness when beneficial and deleterious mutations cosegregate. We perform individual-based simulations of 1D and 2D rangeExpand
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Evidence for polygenic adaptation to pathogens in the human genome.
Most approaches aiming at finding genes involved in adaptive events have focused on the detection of outlier loci, which resulted in the discovery of individually "significant" genes with strongExpand
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Evidence for a genetic discontinuity between Neandertals and 24,000-year-old anatomically modern Europeans
During the late Pleistocene, early anatomically modern humans coexisted in Europe with the anatomically archaic Neandertals for some thousand years. Under the recent variants of the multiregionalExpand
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Mitochondrial DNA and Y‐Chromosome Variation in the Caucasus
We have analyzed mtDNA HVI sequences and Y chromosome haplogroups based on 11 binary markers in 371 individuals, from 11 populations in the Caucasus and the neighbouring countries of Turkey and Iran.Expand
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The population history of northeastern Siberia since the Pleistocene
Far northeastern Siberia has been occupied by humans for more than 40 thousand years. Yet, owing to a scarcity of early archaeological sites and human remains, its population history and relationshipExpand
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