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Amplification of a Cytochrome P450 Gene Is Associated with Resistance to Neonicotinoid Insecticides in the Aphid Myzus persicae
TLDR
The mechanisms underlying resistance to the neonicotinoid insecticides were investigated using biological, biochemical, and genomic approaches and it was suggested that P450-mediated detoxification plays a primary role in resistance, although additional mechanism(s) may also contribute.
The evolution of insecticide resistance in the peach potato aphid, Myzus persicae.
Resistance of insect pests to neonicotinoid insecticides: current status and future prospects.
TLDR
Strategies to combat neonicotinoid resistance must take account of the cross-resistance characteristics of these mechanisms, the ecology of target pests on different host plants, and the implications of increasing diversification of the neonicsotinoid market due to a continuing introduction of new molecules.
A nicotinic acetylcholine receptor mutation conferring target-site resistance to imidacloprid in Nilaparvata lugens (brown planthopper).
TLDR
Evidence was obtained that demonstrates that mutation Y151S is responsible for a substantial reduction in specific [3H]imidacloprid binding, providing direct evidence for the occurrence of target-site resistance to a neonicotinoid insecticide.
Mutation of a nicotinic acetylcholine receptor β subunit is associated with resistance to neonicotinoid insecticides in the aphid Myzus persicae
TLDR
This study finds a single point mutation in the loop D region of the nAChR β1 subunit of the resistant clone of M. persicae, causing an arginine to threonine substitution (R81T) and provides further validation of exisiting models of neonicotinoid binding and selectivity for insect nA ChRs.
Mitochondrial heteroplasmy and the evolution of insecticide resistance: Non-Mendelian inheritance in action
TLDR
An example of insecticide resistance in an arthropod pest (Tetranychus urticae) being controlled by mtDNA and on its inheritance in a heteroplasmic mite strain is reported, providing a rare insight into non-Mendelian mechanisms of mitochondrial inheritance and evolution relevant to anticipating and understanding the development of other mitochondrially encoded adaptations in arthropods.
Nicotinic acetylcholine receptors: targets for commercially important insecticides
TLDR
There is growing evidence for the evolution of resistance to insecticides that act on nAChRs, including neonicotinoid insecticides, which are used extensively in both crop protection and animal health applications.
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