Insights into opioid action in the intestinal tract.
- A. De Luca, I. Coupar
- BiologyPharmacology and Therapeutics
- 1996
Activation of 5‐HT3 receptors in the rat and mouse intestinal tract: a comparative study
It is concluded that functional 5‐ HT3 receptors are present in nerves along the length of the rat and mouse intestinal tract and the mouse proximal colon was found to discriminate 5‐HT3 receptor agonist profiles better than any other region in the rat or mouse.
Comparison of opioid receptor distributions in the rat central nervous system.
- A. C. Gray, I. Coupar, P. White
- BiologyLife Science
- 10 July 2006
Antiinflammatory screening of the medicinal plant Gynura procumbens
- M. Iskander, Y. Song, I. Coupar, W. Jiratchariyakul
- Chemistry, MedicinePlant foods for human nutrition
- 2002
Attempts were made to verify the folkmedicinal claim that the crude ethanolic extract of G. procumbens has antinflammatory action and torelate the activity to particular fractions using acroton oil-induced mouse ear inflammation model.
A comparative study of functional 5‐HT4 receptors in human colon, rat oesophagus and rat ileum
- P. Mclean, I. Coupar, P. Molenaar
- Biology, MedicineBritish Journal of Pharmacology
- 1 May 1995
The studies have shown that the human colon, rat oesophagus and rat ileum contain functional 5‐HT4 receptors and the 5‐ HT4 receptor agonists displayed differences in these tissues making it to be cautious when extrapolating from animal to human tissue.
Comparison of opioid receptor distributions in the rat ileum.
- A. C. Gray, I. Coupar, P. White
- BiologyLife Science
- 28 February 2006
Human 5–HT4 and 5–HT7 Receptor Splice Variants: Are they Important?
- I. Coupar, P. Desmond, H. Irving
- BiologyCurrent Neuropharmacology
- 30 November 2007
This review examines the functional relevance and known and candidate signalling systems that allow for splice variant specific responses include GPCR interacting proteins (GIPs) and G PCR receptor kinases (GRKs) which are examined.
Demonstration of 5-HT3 receptor function and expression in the mouse bladder
- N. Chetty, I. Coupar, R. Chess-Williams, K. Kerr
- BiologyNaunyn-Schmiedeberg's Archives of Pharmacology
- 3 July 2007
5-HT mediates enhanced neurogenic contractions of the mouse bladder muscle by an action at 5-HT3 receptors located prejunctionally on nonsensory nerve elements.
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