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Effects of chronic treatment with ethanol and withdrawal of ethanol on levels of dopamine, 3,4-dihydroxyphenylacetic acid and homovanillic acid in the striatum of the rat. Influence of
The intraperitoneal injection of midazolam produced statistically significant decreases in levels of DOPAC and ratio of turnover values in rats 48 hr after withdrawal of ethanol, with respect to control and chronically ethanol-treated animals, in contrast to the absence of changes produced when injecting thiopental or somatostatin. Expand
Studies on the neuroprotective effect of the enantiomers of AR-A008055, a compound structurally related to clomethiazole, on MDMA ("ecstasy")-induced neurodegeneration in rat brain
The data suggest that drugs which increase GABAA receptor channel opening are neuroprotective against MDMA-induced damage, and appears to be solely due to its action on body temperature. Expand
Effects of an acute dose of ethanol on dopaminergic and serotonergic systems from rat cerebral cortex and striatum.
The results point to several ethanol-linked alterations in central serotonergic and dopaminergic systems in rat striatal systems. Expand
Effects of chronic treatment with ethanol and withdrawal on levels of monoamines in rat cerebral cortex and striatum. Influence of midazolam, thiopenthal and somatostatin.
The effects of chronic ethanol treatment and withdrawal on cortical and striatal levels of several neurotransmitters and the influence of barbiturate, benzodiazepine and somatostatin has been studied in order to establish possible cross-interactions. Expand
Dihydropyridines on guinea-pig ileum.
Nimodipine and nitrendipine produced a similar and potent inhibitory effect of the contractile responses induced in the guinea-pig ileum and nisoldipine resulted to be the most active agent. Expand