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Treatment of osteomyelitis with teicoplanin-encapsulated biodegradable thermosensitive hydrogel nanoparticles.
Osteomyelitis characterized by an inflammatory response often leads to bone loss and the spread of bacterial infection to surrounding soft tissues. To overcome the side effects induced by the… Expand
Mn2 + improves surfactin production by Bacillus subtilis
Surfactin productivity by Bacillus subtilis was increased from 0.33 g l−1 to 2.6 g l−1 by adding 0.01 mM Mn2+ to a defined glucose medium. The final yield exceeded that of most reported values for… Expand
Enhancement of surfactin production in iron-enriched media by bacillus subtilis ATCC 21332
Abstract Production of a lipopeptide surfactant, surfactin, by Bacillus subtilis ATCC 21332 was highly enhanced when iron concentration in the medium was raised from 4 μ m to the few m m level. This… Expand
Chondrocytes culture in three-dimensional porous alginate scaffolds enhanced cell proliferation, matrix synthesis and gene expression.
- Y. Lin, Chi-Nan Yen, Y. Hu, Yung-Chih Wu, Chun-Jen Liao, I. Chu
- Materials Science, Medicine
- Journal of biomedical materials research. Part A
For the limited availability of autologous chondrocytes, a cultured system for expansion in vitro until sufficient cells are obtained must be developed. These cells must maintain their chondrocyte… Expand
Chemical and physical properties of bone cement for vertebroplasty.
Vertebral compression fracture is the most common complication of osteoporosis. It may result in persistent severe pain and limited mobility, and significantly impacts the quality of life.… Expand
Simultaneous estimation of chlorophyll a and lipid contents in microalgae by three-color analysis.
- Chia-Hung Su, Chun-Chong Fu, +4 authors Wen-Teng Wu
- Biology, Medicine
- Biotechnology and bioengineering
- 1 March 2008
A method of rapid determination of chlorophyll a and lipid contents of microalgae based on colorimetric analysis of the digital images of the microalgae is proposed. The color variation of microalgae… Expand
Type II collagen-chondroitin sulfate-hyaluronan scaffold cross-linked by genipin for cartilage tissue engineering.
- Chih-Sheng Ko, Jui-Pin Huang, Chia-Wen Huang, I. Chu
- Chemistry, Medicine
- Journal of bioscience and bioengineering
- 1 February 2009
Owing to of the limited repair capacity of articular cartilage, it is essential to develop tissue-engineered cartilage for patients suffering from joint disease. Chondroitin sulfate (CS) and… Expand
Inhibitory effect of p-hydroxybenzyl alcohol on tyrosinase activity and melanogenesis.
Tyrosinase is a key enzyme catalyzing the rate-limiting step for the biosynthesis pathway of melanin pigment, which is the most important determinant of the color of skin. Inhibiting tyrosinase and… Expand
Characterization of serum-free ex vivo-expanded hematopoietic stem cells derived from human umbilical cord blood CD133(+) cells.
- C. Yao, Y. Feng, X. Lin, I. Chu, Tzu-Bou Hsieh, S. Hwang
- Medicine, Biology
- Stem cells and development
- 7 March 2006
The development of ex vivo expansion of hematopoietic stem cells (HSCs) is a promising approach to restore the required bone marrow function of patients with hematological disorders. Previously, we… Expand
Enhanced expression of various exogenous genes in recombinant Chinese hamster ovary cells in presence of dimethyl sulfoxide
Dimethyl sulfoxide (DMSO) (1% v/v) stimulated stable transformed Chinese hamster ovary (CHO) cells to synthesize different recombinant proteins and repress their proliferation rate. The expressions… Expand