Trends in Biotechnology
- I. Chibata, T. Tosa
- Engineering
- 1982
Glycolytic pathway as an ATP generation system and its application to the production of glutathione and NADP
- K. Murata, K. Tani, J. Kato, I. Chibata
- Biology, Engineering
- 1 July 1981
Conversion of Glycerol to Dihydroxyacetone by Immobilized Whole Cells of Acetobacter xylinum
- K. Nabe, N. Izuo, S. Yamada, I. Chibata
- Biology, EngineeringApplied and Environmental Microbiology
- 1 December 1979
Enzymatic production of dihydroxyacetone (DHA) was studied by immobilization of the whole cells of acetic acid bacteria capable of oxidizing glycerol to DHA. Acetobacter xylinum A-9 cells immobilized…
Production of l-Phenylalanine from trans-Cinnamic Acid with Rhodotorula glutinis Containing l-Phenylalanine Ammonia-Lyase Activity
- S. Yamada, K. Nabe, N. Izuo, Katsuhiko Nakamichi, I. Chibata
- Biology, ChemistryApplied and Environmental Microbiology
- 1 November 1981
The enzyme activity was kept stable for a relatively long time during cultivation by the addition of l-isoleucine and may provide a rapid and practical way to produce l-phenylalanine useful as an essential amino acid.
Continuous production of L‐citrulline by immobilized Pseudomonas putida cells
- Kozo Yamamoto, Tadashi Sato, T. Tosa, I. Chibata
- Biology, EngineeringBiotechnology and Bioengineering
- 1 December 1974
The microbial cells of Pseudomonas putida ATCC 4359 were immobilized by entrapment in a polyacrylamide gel lattice and the permeability of substrate or product through the cell wall und the heat stability of the enzyme were increased by immobilization of the cells.
Basic studies for continuous production of L-aspartic acid by immobilized Escherichia coli cells.
- T. Tosa, T. Sato, T. Mori, I. Chibata
- Biology, EngineeringApplied microbiology
- 1 May 1974
Conditions for continuous production of L-aspartic acid from ammonium fumarate were investigated using a column packed with immobilized Escherichia coli cells entrapped in a polyacrylamide gel lattice and the immobilized cell column was very stable.
Lentinacin: a new hypocholesterolemic substance inLentinus edodes
- I. Chibata, K. Okumura, S. Takeyama, K. Kotera
- Chemistry, MedicineExperientia
- 15 December 1969
Aus dem Speisepilz «Shiitake» (Lentinus edodes) wurde ein new Adeninderivat isoliert und Lentinacin genannt, which senkt den Cholesterinspiegel bei Ratten.
Biosynthesis of norvaline, norleucine, and homoisoleucine in Serratia marcescens.
- M. Kisumi, M. Sugiura, I. Chibata
- Biology, ChemistryJournal of Biochemistry (Tokyo)
- 1 August 1976
Norvaline and homoisoleucine are considered to be formed fromalpha-ketobutyrate and alpha-keto-beta-methylvalerate by the leucine biosynthetic enzymes, and this view was confirmed by the findings that a norvaline accumulator could be obtained by derivation of theLeucine accumulators into an isoleucin-valine auxotroph.
Enzymatic production of urocanic acid by Achromobacter liquidum.
- T. Shibatani, N. Nishimura, K. Nabe, T. Kakimoto, I. Chibata
- Biology, ChemistryApplied microbiology
- 1 April 1974
Yields of isolated urocanic acid of over 92% from L-histidine were easily attainable and when the culture of Achromobacter liquidum was added to DL- histidine, D-histazine and uro canic acid were simultaneously obtained in high yields.
Pathway for isoleucine formation form pyruvate by leucine biosynthetic enzymes in leucine-accumulating isoleucine revertants of Serratia marcescens.
- M. Kisumi, S. Komatsubara, I. Chibata
- Biology, ChemistryJournal of Biochemistry (Tokyo)
- 1 July 1977
Leaky revertants isolated from isoleucine auxotrophs of Serratia marcescens mutant resistant to alpha-aminobutyric acid are concluded to be synthesized from alpha-ketobutyrate via citramalate formed from pyruvate annd acetyl-coenzyme A by leucine biosynthetic enzymes, as a result of desensitization of alpha-isopropylmalate synthetase to feedback inhibition.
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