• Publications
  • Influence
Mutations in the p53 gene are frequent in primary, resected non-small cell lung cancer. Lung Cancer Study Group.
The p53 gene has been implicated as a tumor suppressor gene with mutations found in common human cancers. We examined 51 early stage, primary, resected non-small cell lung cancer specimens using anExpand
  • 526
  • 8
Polymorphism at codon 213 within the p53 gene.
This report describes a rare polymorphism at codon 213 (silent alteration of CGA to CGG) within the coding region of the p53 gene. The rare polymorphic allele was present in six cases out of 189 lungExpand
  • 151
  • 4
Multiple oral squamous epithelial lesions: are they genetically related?
The development of second primary tumors (SPTs) in patients with head and neck squamous cell carcinoma (HNSCC) has become an increasingly important factor in clinical treatment decison. Currently,Expand
  • 97
  • 3
Identification of intronic point mutations as an alternative mechanism for p53 inactivation in lung cancer.
The p53 gene initially was thought to be an oncogene, but recent evidence suggests that wild-type p53 can function as a tumor suppressor gene in lung, colon, and breast cancer as well as less commonExpand
  • 138
  • 2
CYP2A6 gene deletion reduces oral cancer risk in betel quid chewers in Sri Lanka.
We investigated the relationship between inter-individual difference in CYP2A6 genotype and susceptibility to oral cancer among habitual betel quid chewers in a Sri Lanka population. A total of 286Expand
  • 70
  • 2
  • PDF
Specific p53 mutations predict poor prognosis in oral squamous cell carcinoma.
In this study, we focused on p53 mutations in specific regions, including DNA-binding surface regions, to clarify the correlation between mutations within the specific regions of p53 and clinicalExpand
  • 54
  • 2
Development of the self-efficacy scale for maternal oral care.
PURPOSE This study's purpose was to develop a task-specific self-efficacy scale for maternal oral care (SESMO) with reliability and validity. METHODS A draft scale consisting of 36 items wasExpand
  • 16
  • 2
High prevalence of hepatitis C virus antibody and RNA in patients with head and neck squamous cell carcinoma
We have investigated the prevalence of hepatitis C virus (HCV) infection in patients with head and neck squamous cell carcinoma (SCC) in Japan. This study design was based on a prospective cohort atExpand
  • 17
  • 2
Hereditary and acquired p53 gene mutations in childhood acute lymphoblastic leukemia.
The p53 gene was examined in primary lymphoblasts of 25 pediatric patients with acute lymphoblastic leukemia by the RNase protection assay and by single strand conformation polymorphism analysis inExpand
  • 99
  • 1
  • PDF
Occurrence of p53 gene abnormalities in gastric carcinoma tumors and cell lines.
We explored the state of the p53 gene in gastric cancer. Using one or more methods, we examined 15 specimens from primary carcinomas (14 tumors, one cell line), five cell lines derived fromExpand
  • 128
  • 1