I. Chen

Publications383
h-index40
Citations6,660
Highly Influential Citations182
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Anti-AIDS agents, 11. Betulinic acid and platanic acid as anti-HIV principles from Syzigium claviflorum, and the anti-HIV activity of structurally related triterpenoids.
TLDR
Evaluation of anti-HIV activity with eight derivatives of 1 revealed that dihydrobetulinic acid was also a potent inhibitor of HIV replication, and there was no apparent correlation between anti-hIV activity and the inhibition of PKC among these compounds.
Secondary metabolites from the endophytic fungus Biscogniauxia formosana and their antimycobacterial activity
Anti-inflammatory endiandric acid analogues from the roots of Beilschmiedia tsangii.
TLDR
Bioassay-guided fractionation of roots of Beilschmiedia tsangii led to the isolation of six new endiandric acid analogues, which exhibited potent iNOS inhibitory activity and were determined by spectroscopic techniques.
Secondary metabolites and cytotoxic activities from the endophytic fungus Annulohypoxylon squamulosum
A Novel Dimeric Coumarin Analog and Antimycobacterial Constituents from Fatoua pilosa
TLDR
One novel dimeric coumarin analog, fatouapilosin, together with 18 known compounds, have been isolated from the whole plants of Fatoua pilosa and exhibited the strongest antimycobacterial activities against Mycobacterium tuberculosis H37Rv.
Coumarins and antiplatelet constituents from the root bark of Zanthoxylum schinifolium.
TLDR
Among the isolates, terpenyl-coumarins and furoquinolines were the active constituents with antiplatelet aggregation in vitro and collinin showed significant anti-HBC DNA replication activity.
Novel epoxyfuranoid lignans and antitubercular constituents from the leaves of Beilschmiedia tsangii.
TLDR
Three new epoxyfuranoid lignans and four known compounds have been isolated from the leaves of Beilschmiedia tsangii and exhibited potent antitubercular activities against Mycobacterium tuberculosis 90 - 221387 in vitro.
Coumarins and antiplatelet aggregation constituents from Formosan Peucedanum japonicum.
(-)-Epigallocatechin gallate inhibition of osteoclastic differentiation via NF-kappaB.
Two new sesquiterpenoids and anti-HIV principles from the root bark of Zanthoxylum ailanthoides.
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