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Transdermal delivery of mixnoxidil with block copolymer nanoparticles.
TLDR
Confocal microscopy coupled with in vivo and in vitro skin permeation results demonstrated that nanoparticles containing solutes penetrated mainly via shunt routes like hair follicles, resulting in skin absorption of solutes. Expand
Biflavonoids isolated from Selaginella tamariscina regulate the expression of matrix metalloproteinase in human skin fibroblasts.
The methanol extract from Selaginella tamariscina significantly inhibited UV irradiation induced activity of matrix metalloproteinase-1 (MMP-1) in primary fibroblasts from human skin. Using theExpand
The effects of a novel synthetic retinoid, seletinoid G, on the expression of extracellular matrix proteins in aged human skin in vivo.
TLDR
Seletinoid G is a novel synthetic retinoid, which has little the side effect of skin irritation after topical application and was found to inhibit UV-induced collagen deficiency in young skin. Expand
Regioselective hydroxylation of isoflavones by Streptomyces avermitilis MA-4680.
  • C. Roh, S. Seo, +7 authors B. Kim
  • Chemistry, Medicine
  • Journal of bioscience and bioengineering
  • 1 July 2009
TLDR
Ketoconazole significantly inhibited the ortho-hydroxylation activity of daidzein, suggesting that cytochrome P450 enzymes putatively play roles in regiospecific daidzesin hydroxylations. Expand
The extract of Thujae occidentalis semen inhibited 5alpha-reductase and androchronogenetic alopecia of B6CBAF1/j hybrid mouse.
TLDR
The inhibitory activity of TOS extract for 5alpha-reductase type 2 is demonstrated and its biological action in two animal models is demonstrated, suggesting that TOS Extract would be used as an effective agent for male pattern baldness by modifying androgen conversion. Expand
Simultaneous determination of two Amadori compounds in Korean red ginseng (Panax ginseng) extracts and rat plasma by high-performance anion-exchange chromatography with pulsed amperometric detection.
A new simple, rapid and sensitive high-performance anion-exchange chromatography method with pulsed amperometric detection (HPAEC-PAD) was developed and validated for the simultaneous determinationExpand
Antioxidant effects of Origanum majorana L. on superoxide anion radicals
A purified compound with antioxidant properties (28 mg), T3b, was isolated from a methanol extract (10 g) of Origanum majorana L. by sequential procedures, with silica gel column, thin-layer, andExpand
[4-t-butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) inhibits SCF/c-kit signaling in 501mel human melanoma cells and abolishes melanin production in mice and brownish guinea pigs.
TLDR
Results indicate that phenyl-imidazole sulfonamide derivatives are potent c-kit inhibitors and might be used as skin-whitening agents. Expand
Stabilization of papain and lysozyme for application to cosmetic products
For cosmetic applications, papain or lysozyme was conjugated to a soluble biopolymer produced by Schizophyllum commune. Stability of the conjugated enzymes were significantly enhanced, such that moreExpand
Synthesis of silver/polymer colloidal composites from surface-functional porous polymer microspheres
Abstract This study presents a different colloidal silver (Ag)/polymer system where Ag nanoparticles are deposited uniformly onto surface-functional porous poly(ethylene glycolExpand
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