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A comparison of the efficacy and acceptability of the Copper-7 intrauterine device following immediate or delayed insertion after first-trimester therapeutic abortion.
The advantages of immediate postabortion insertion include the necessity for a single clinic visit for both extraction and insertion, and thus a single episode of discomfort; immediate contraceptive protection; and acceptance by a larger number of women. Expand
Pharmacology, electrophysiology, and pharmacokinetics of mexiletine.
Mexiletine is a class I antiarrhythmic agent that is active after both oral and intravenous administration and similar in structure and activity to lidocaine and may aggravate preexisting impairment of impulse generation and conduction. Expand
Potential Applications of Free Drug Level Monitoring in Cardiovascular Therapy†
Careful studies relating bound and free drug concentration to pharmacological response may provide the clinician with a better guide to therapy, and enhance the usefulness of these drugs. Expand
Effects of Oral Contraceptives on Lipoprotein Lipids: A Prospective Study
- M. Powell, A. Hedlin, I. Cerskus, G. Kakis, D. Prudham, P. Rosenrot
- Obstetrics and gynecology
- 1 June 1984
Oral contraceptives should be regarded as differing in their potential for altering lipoprotein lipid levels, and the absolute steroid content of an oral contraceptive is not the only indicator of its effects upon lipid metabolism. Expand
Antiarrhythmic Therapy: Clinical Pharmacology Update
An awareness of the possible contribution of these factors in the use of antiarrhythmic agents is invaluable in both the choice of agent and the establishment of an optimum benefit‐to‐risk ratio for the patient. Expand
The effects of a hydroperoxide compound, structurally related to ASA, on arachidonic acid metabolism by various tissues and PMN accumulation in an in vivo model
Use of the cu-7 device in a family planning clinic.
- J. Bouchard, R. Albert, I. Cerskus
- Canadian family physician Medecin de famille…
- 1 November 1980
The experience of 707 women undergoing a first insertion of the Cu-7® at the Family Planning Clinic, Edmundston, has been assessed and removal for pain among nulliparous women were significantly more frequent than among parous patients. Expand
Antiinflammatory properties of a hydroperoxide compound, structurally related to acetylsalicylic acid
3-Hydroperoxy-3-methylphthalide, a structural analog of acetylsalicylic acid, was found to have some antiinflammatory properties which are distinct from those of ASA. Expand
Atenolol in the treatment of essential hypertension.
By virtue of its hydrophilicity, cardioselectivity and long half-life, atenolol appears to be a suitable and well-tolerated beta-blocker in the majority of patients. Expand
Relationship of inhibition of prostaglandin synthesis in platelets to anti-aggregatory and anti-inflammatory activity of some benzoic acid derivatives
There is not a good correlation between ability to inhibit platelet PG synthesis, anti-aggregatory activity and anti-inflammatory activity, and multiple mechanisms of action, differing sensitivities of various tissue PG synthetases, or unidentified factors could be involved. Expand