I. Beucler

Publications72
h-index21
Citations3,409
Highly Influential Citations127
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Mutations in PCSK9 cause autosomal dominant hypercholesterolemia
Autosomal dominant hypercholesterolemia (ADH; OMIM144400), a risk factor for coronary heart disease, is characterized by an increase in low-density lipoprotein cholesterol levels that is associated… Expand
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Plant Sterol-Enriched Margarine Lowers Plasma LDL in Hyperlipidemic Subjects with low Cholesterol Intake: Effect of Fibrate Treatment
Abstract Phytosterols, found in fat-soluble fractions of plants, chemically resemble cholesterol and inhibit cholesterol absorption in the small intestine. Phytosterol consumption in human subjects… Expand
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Smaller LDL particle size in women with polycystic ovary syndrome compared to controls
OBJECTIVE Women with polycystic ovary syndrome (PCOS) have an increased risk of cardiovascular disease. The contribution of lipid abnormalities to this higher risk, in particular atherogenic… Expand
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Immunological detection of low-density lipoproteins modified by malondialdehyde in vitro or in vivo.
We describe an ELISA technique able to recognize malondialdehyde-modified low-density lipoproteins (LDL). For this purpose we produced antibodies to malondialdehyde-LDL, specific for the… Expand
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Blood oxidative stress markers are unreliable markers of hepatic steatosis
Non‐alcoholic fatty liver disease (NAFLD) and viral hepatitis are associated with hepatic oxidative stress, which is partially dependent on the amount of hepatic fat.
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APOE: A potential marker of disease progression in ALS
Abstract—Although documented in AD, the role of APOE remains unclear in ALS. APOE phenotype and plasma levels were measured in 403 patients with ALS and were correlated with clinical parameters and… Expand
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Low lipolytic enzyme activity in patients with severe hypertriglyceridemia on highly active antiretroviral therapy.
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[Structure and metabolism of plasma lipoproteins].
Blood plasma contains lipoproteins of which the structure and the composition are not constant during the time and that depend on their metabolic evolution from their synthesis rate in intestine or… Expand
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Relationship between thyroid hormones and plasma D-dimer levels.
High serum levels of cholesterol and triglycerides are risk factors for coronary heart disease and are strongly related to several haemostatic parameters. Thyroid disorders are a frequent feature in… Expand
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Infantile phytanic acid storage disease, a possible variant of Refsum's disease: Three cases, including ultrastructural studies of the liver
Three cases of phytanic acid storage disease with symptoms during the first months of life are reported. Hepatomegaly, facial dysmorphia, growth and/or mental retardation and osteopenia were observed… Expand
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