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Ethanol consumption and resistance are inversely related to neuropeptide Y levels
Genetic linkage analysis of rats that were selectively bred for alcohol preference identified a chromosomal region that includes the neuropeptide Y (NPY) gene. Alcohol-preferring rats have lowerExpand
Central infusions of leptin and GLP-1-(7-36) amide differentially stimulate c-FLI in the rat brain.
Recently, glucagon-like peptide-1-(7-36) amide (GLP-1) and leptin have been implicated in the regulation of food intake. In the present study, we compared the effects of third ventricularExpand
High Ethanol Consumption and Low Sensitivity to Ethanol-Induced Sedation in Protein Kinase A-Mutant Mice
Both in vitro and in vivo evidence indicate that cAMP-dependent protein kinase (PKA) mediates some of the acute and chronic cellular responses to alcohol. However, it is unclear whether PKA regulatesExpand
Taste aversion learning: a contemporary perspective.
Food aversion learning has attracted widespread interest because it is a highly adaptive, powerful type of learning with both practical and theoretical ramifications. It has features that make itExpand
Central infusion of GLP-1, but not leptin, produces conditioned taste aversions in rats.
Leptin (ob protein) and glucagon-like peptide-1-(7-36) amide (GLP-1) are peptides recently proposed to be involved in the regulation of food intake. Although the ability of exogenous leptin and GLP-1Expand
Novel tastes elevate c-fos expression in the central amygdala and insular cortex: implication for taste aversion learning.
Taste novelty strongly modulates the speed and strength of taste aversion conditioning. To identify molecular signals responsive to novel tastes, immunostaining for c-fos protein (Fos-likeExpand
c-Fos induction in response to a conditioned stimulus after single trial taste aversion learning
Taste aversion conditioning is characterized by its prompt acquisition despite the introduction of long delays between CS (taste) and UCS (toxic drug). Although the dramatic changes in behavioralExpand
Area postrema mediation of physiological and behavioral effects of lithium chloride in the rat
The area postrema (AP), a chemoreceptor trigger zone for nausea and vomiting, has been implicated in taste aversion conditioning with LiCl. In addition to taste aversion acquisition, the presentExpand
Visualizing stimulus convergence in amygdala neurons during associative learning
A central feature of models of associative memory formation is the reliance on information convergence from pathways responsive to the conditioned stimulus (CS) and unconditioned stimulus (US). InExpand
Learned taste aversions in children receiving chemotherapy.
Children with neoplastic diseases were offered an unusual ice cream before their drug treatments. Patients experiencing gastrointestinal toxicity due to the drugs were subsequently less likely toExpand
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