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The oxidation behavior of Y-931, a potent atypical antipsychotic drug, was compared with that of clozapine and olanzapine. In two enzymatic systems (horseradish peroxidase (HRP)/glutathione (GSH) and HRP/H(2)O(2)/GSH) which generate thiyl radicals, clozapine markedly strengthened the electron paramagnetic resonance (EPR) signal for the radical. Olanzapine,(More)
In Japan, the "bedridden state" is one of the most serious problems the aged face, and it is becoming a social problem. The main causes of the bedridden state are cerebrovascular disorders and bone fractures following falls. The purpose of this study was to predict risk factors for falls and resultant bone fracture due to osteoporosis. We explored mobility(More)
For consumer electronics and appliances, rectifier circuits of the capacitor input type are generally used. The various harmonics generated within such a power system become a serious problem. Various studies to reduce these effects have been presented so far. However, most of these employ switching devices, such as MOSFETs and the like. Removing the need(More)
Chiral bis(alpha, alpha-diphenyl-2-pyrrolidinemethanol) carbonate (DPP(2).H(2)CO(3)) is a useful asymmetric auxiliary for the asymmetric borane reduction of prochiral ketones. Chiral DPP(2).H(2)CO(3) is recoverable from the reaction and directly reusable for the reaction. The intermediate of KUR-1246, which we are developing as a new uterine relaxant, was(More)
OBJECTIVE To investigate the influence of dentures wearing on the parameters of physical fitness, particularly on agility and balance function in elderly people. DESIGN A case control study. SETTING Motohachiohjimachi, Hachiohji, Tokyo, Japan. METHODS Motor reaction time was measured in the presence and absence of dentures in the subjects who were 1)(More)
The line impedance could be measured by means of only passive elements such as inductors or resistors, that is presented at first. However, as the voltage and current used for the measurement are increased, the size of the inductor or resistor being used also needs to be increased, so in practice it would be virtually impossible to make an accurate(More)