I Villares Alvarez

Learn More
The introduction of reduced-intensity conditioning (RIC) has enabled the role of allogeneic transplantation to be re-evaluated in Hodgkin lymphoma (HL). While T-cell depletion reduces graft-versus-host disease (GvHD), it potentially abrogates graft-versus-tumour activity and increases infective complications. We compared the results in 67 sibling donor(More)
We report the results of reduced-intensity conditioning allogeneic stem cell transplantation (allo-RIC) in patients with advanced Hodgkin lymphoma (HL). Forty patients with relapsed or refractory HL were homogeneously treated with an RIC protocol (fludarabine 150 mg/m(2) intravenously plus melphalan 140 mg/m(2) intravenously) and cyclosporin A and(More)
More than 80% of children with growth hormone deficiency (GHD) respond with a rise in growth hormone levels when given 1 microgram/kg body weight of growth hormone-releasing hormone (GHRH) in an i.v. bolus. We conducted a study to determine whether the failure of the remaining 20% to respond to GHRH is due to a pituitary deficiency or a secondary effect(More)
Marked hyperamylasaemia associated with an amylase-producing multiple myeloma appears to be a fairly unusual phenomenon. The present report describes a fatal case of multiple myeloma associated with paraneoplastic hyperamylasaemia without evidence of pancreatic or salivary gland involvement. Serum and urine amylase levels paralleled the myeloma response to(More)
containing chromatin-remodeling complex in adult-type erythroid cells. Mol Cell Biol 2000; 20: 7572–7582. 15 Song C, Gowda C, Pan X, Ding Y, Tong Y, Tan BH et al. Targeting casein kinase II restores Ikaros tumor suppressor activity and demonstrates therapeutic efficacy in high-risk leukemia. Blood 2015; 126: 1813–1822. This work is licensed under a Creative(More)
Sickle cell disease (SCD) is the most frequent hereditary disorder in Cuba. The incidence of sickle cell trait is 13, 25 in blacks, 0, 65 in whites and 3, 085 for the general population. There are 4000 sickle cell patients distributed throughout the country, with a greater prevalence in Havana city and in the South-Western provinces. In spite of the fact(More)
  • 1