I. Reilly

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Up until now, the exact mechanism by which neuromodulation using sacral nerve stimulation works still remains unknown. Recent studies of pelvic floor contraction during peripheral nerve evaluation (PNE) have shown that several muscle responses are reflexly mediated. However, whether these reflexes originate from a segmental level within the sacral spinal(More)
Renal failure occurs in about 50% of cases of myeloma and may be a presenting feature of the disease. It is known to be a poor prognostic sign, with median survival of 13 months (MRC, 1984) or less (Cavo, 1986) compared to 30-36 months for myeloma as a whole (Editorial, 1988). In about half the patients renal failure is reversible following initial(More)
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