I. P. Kovel'man

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Powerful irreversible inhibitors of monoamineoxidase (MAO) (EC 1.4.3.4) have been discovered among 6-, 7-, and 8-(N-methyl-N-2-propynylaminomethyl)quinolines substituted in the carbocyclic ring. These act at concentrations of 10-7-10 -9 M and the introduction of halogen atoms increases their selectivity towards MAO of type A [2]. With the aim of studying(More)
The high effectiveness of some acetylenic inhibitors [1, 13, 14] is a stimulation to carry out searches for new monoamine oxidase (MAO) inhibitors among newly synthesized derivatives of 2-propynylamines. The present work has been done as an extension to earlier investigations that are connected with the synthesis and study of MAO inhibitors, derivatives of(More)
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