I N Ianvareva

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In anesthetized male rats the arterial blood pressure in femoral artery and electrocardiogram in standard leads were recorded uninterruptedly for 1-1.5 h under conditions of acute nitrite intoxication produced by a subcutaneous injection of water solution of sodium nitrite (donor of nitric oxide) at concentrations of 10, 30, and 50 mg/kg body mass. Results(More)
The characteristics of human cerebral blood flow were estimated during the implementation of the diving response, simulated by complex cold-hypoxic-hypercapnic exposure (CHHE), and under the influence of separate cold, hypercapnic and hypoxic stimuli. Was studied 18 people aged 18-22 years who had no special training. Cerebral blood flow was recorded by(More)
Redox-reactions of flavine (FN) and pyridine (PN) nucleotides of the cell to guthimine were studied by the method of fluorescent microscopy without using any stains. The comparison was made of the kinetics of fluorescence intensity of FN and PN of the Retzius intact neuron under the action of guthimine, oxaloacetate, nembutal and succinate. It is suggested(More)
The effects of antihypoxants gutimine and amtisole on oxygen consumption by the intact nerve cell of the invertebrate and the activity of NADN-DH and SDH-dependent ways of oxidation in the cell were studied. Under normoxia gutimine inhibited the nerve cell respiration and decreased the activity of NADN-DN and SDH-dependent ways of oxidation by 15% and 5%(More)
In semi-aquatic mammals (minks and muskrats) significant changes were found to occur in the leukocyte formula during adaptation to hypoxia, as compared with non-adapted rats and mice, although no increase in lipid peroxidation was found in any of their organs. This latter finding seems to be due to simultaneously enhanced activities of superoxide dismutase(More)
Asphyxia produced by discontinuing of artificial respiration for 3-5 min in curarized cats, was well tolerated by some neurons of the cerebral and hypothalamus cortex even when repeated a few times with the interval between asphyxias from 40 to 60 min. In most cases neurons even increased their resistance against subsequent effect of acute oxygen(More)
Responses of the cardio-vascular system and bioenergetic metabolism were studied in the heart tissue in apnoea in naturally adapted to diving musk-rats and unadapted rats and mice. A sharp bradycardia was shown to develop in former animals in arresting a breathing as well an increase in the neutrophils contents in the blood. The data obtained suggest that(More)
In anesthetized cats, spontaneous activity was recorded in neurons of the anterior, supraoptic, lateral, ventro-medial and posterior nuclei of the hypothalamus under conditions of oxygen deficit induced by the blood loss or discontinuation of artificial respiration. Phases of activation and suppression of electric activity of different hypothalamic nuclei(More)