I Marchenko-Bouer

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An educational history, corroborated by records where available, was obtained on 54 of the 58 adult offspring of 17 bipolar manic-depressives. The offspring were also interviewed and psychiatric status was ascertained. Primary and other affective disorder in the offspring was not associated with a lower IQ or lower ultimate educational attainment than that(More)
Forty-eight of the 50 living adult offspring of 16 bipolar patients were interviewed. Data was available on the 2 other offspring, who had previously suicided. One half of the offspring met criteria for psychiatric illness, the majority of which was either primary affective or other affective disorder. The mean age of onset of illness was middle to late(More)
The authors report on the case ascertainment phase of a pedigree study of patients with bipolar affective disorder. The nature of the research interview, which necessarily probes for symptoms and signs of affective disorder, appeared to have a provocative effect on some subjects by exposing heavily defended conflicts related to the expression of affect.(More)
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