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C-CAM is a Ca(2+)-independent cell adhesion molecule (CAM) that mediates intercellular adhesion of isolated rat hepatocytes. It is widely distributed in epithelia, where its presence both at lateral cell borders and on apical cell surfaces suggests that it may have diverse biological functions. Two major isoforms, C-CAM1 and C-CAM2, which differ in the(More)
The Physiological Society was founded in 1876 in response to the report of a Royal Commission on the use of animals in research, which was expected to lead to legislation. John Bourdon Sanderson invited nineteen physiologists to his house "for the purpose of considering whether any, or what steps ought to be taken with reference to the Recommendations of(More)
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