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The effects of saikosaponins (a, b(1), b(2), c, d), isolated from Bupleurum Radix, on the induction of differentiation in rat C6 glioma cells were studied. Saikosaponins a and d were shown to inhibit cell proliferation and alter cell morphology. In addition to cytostasis, the enzymatic activities of glutamine synthetase (GS) and 2',3'-cyclic nucleotide(More)
BACKGROUND Better depicting the relationship between antibiotic consumption and evolutionary healthcare-associated infections (HAIs) caused by multidrug-resistant Gram-negative bacilli (MDR-GNB) may help highlight the importance of antibiotic stewardship. METHODOLOGY/PRINCIPAL FINDINGS The correlations between antibiotic consumption and MDR-GNB HAIs at a(More)
BACKGROUND Surgical site infection (SSI) after total knee arthroplasty (TKA) is a catastrophic complication. Administration of prophylactic antibiotics within 60 minutes before surgery is a well-established strategy to prevent SSI. The study is aimed to identify the risk factors for SSI regarding primary TKA in patients with timely administration of(More)
Aeginetia indica Linn. (Guan-Jen-Huang, GJH), a traditional Chinese herb, has the potential to be an immunomodulatory agent. The purpose of this study was to explore the effect of GJH in the treatment of renal cancer. Concentration-effect curves for the influence of GJH on cellular proliferation showed a biphasic shape. Besides, GJH had a synergistic effect(More)
Screening ultrasound (US) is increasingly used as a supplement to mammography in women with dense breasts, and more than 80% of cancers detected by US alone are 1cm or smaller. An adaptive computer-aided diagnosis (CAD) system based on tumor size was proposed to classify breast tumors detected at screening US images using quantitative morphological and(More)
In this paper, we present the power estimation methodologies for the development of a low-power security processor that contains significant amount of logic and memory. For the logic part, we present a highly accurate tool, called <i>PowerMixer</i>. This tool is a refinement of the so-called mixed-level methodology that combines the accuracy of quick SPICE(More)
Due to the high complexity of modern circuit designs, verification has become the major bottleneck of the entire design process. There is an emerging need for a practical solution to reduce the verification time. In manufacturing test, a well-known technique, "design-for-testability", is often used to reduce the testing time. By inserting some extra (More)
Klebsiella pneumoniae (KP), with production of abundant capsular polysaccharide (CPS), is capable of causing invasive syndrome. Environmental glucose stimuli may increase CPS biosynthesis. We aimed to investigate the relationship between glycemic control and KP-mediated invasive syndrome in diabetic patients and the effect of glucose on CPS biosynthesis.(More)
Osteoporosis is a common bone disease in the elderly, which often causes back pain and kyphosis. In Taiwan, 51.9 percent of the elderly over 45 years old need rehabilitation and the demand of wearing orthoses aids in the aging of society has increased significantly. Physicians don't know the rehabilitation effectiveness and the patient compliance behaviors(More)