I. L. Kaimovskii

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significant number of reports addressing refractory epilepsy. However, the definition of refractory epilepsy remains somewhat unclear, which makes it difficult to compare results obtained in different studies and make practical recommendations in relation to drug selection. The treatment of patients with refractory and presumptively refractory epilepsy(More)
The current state of the problem of epileptic seizures developed after ischemic and hemorrhagic stroke is presented. Etiology, pathogenesis risk factors of epileptic seizures and their impact on the course and severity of stroke are reviewed. It has been shown that "early" and "late" epileptic seizures have different mechanisms of development. The authors(More)
We studied the products of nitrosative stress, immunoglobulins, and autoantibodies to nitrated proteins in the liquor of patients during the first day after stroke onset. The level of nitric oxide metabolites, nitrates, and nitrites was significantly increased in the liquor of patients after ischemic stroke only. The activity of NO-synthase and release of(More)
The article presents modern conceptions on instrumental diagnosis, using electroencephalography, of non-convulsive status epilepticus (NCSE) based on a traditional classification and recommendations of the American Clinical Neurophysiology Society (2012). The descriptive diagnostic parameters for the recognition of different changes in the brain electrical(More)
Protein-bound nitrotyrosine is a standard marker of nitrosative stress in vivo, its levels being associated with severity of nitrosative stress in neurological diseases. Using two commercially available antibodies we have developed protocols for an indirect competitive enzyme-linked immunosorbent assay (ELISA) aimed at detecting protein-bound nitrotyrosine.(More)
(CCT) is the cause of 20% of symptomatic and 5% of all cases of epilepsy [23]. In Russia, CCT is the main cause (27.7%) of location-dependent epilepsy in adults [1, 18]. Post-traumatic epilepsy (PTE) is one of the late and most serious complications of CCT. CCT and, hence, the possible risk of PTE, is most common in the age range 15–34 years, where the(More)
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