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The mechanism of length determination in bacteriophage lambda tails is discussed as a model for regulation in protein assembly systems. The lambda tail is a long flexible tube ending in a conical part and a single tail fiber. Its length is exactly determined in the sense that the number of major tail protein (gpV) molecules, which comprise more than 80% of(More)
Helix Geometry and Hydration in A-DNA, B-DNA, and Z-DNA R . E . Dickerson, H. R. Drew, B. N. Conner, M. L. Kopka, and P. E. Pjura Structural Diversity in DNA: From Monomer Structures to Oligonucleotides M. A. Fiswamitra Right-handed and Left-handed Double-helical DNA: Structural Studies A.H.-J . Wang, S. Fujii, J.H. van Boom, and A. Rich Left-handed DNA(More)
Some amino acid substitutions in the major capsid protein (gene E product) of lambda phage are found to cause a defect in DNA packaging. These substitutions permit initiation of DNA packaging and expansion of the prohead. However, cleavage of the concatemer DNA at the cos site takes place only to a very small extent, and the capsid eventually becomes empty.(More)
Missense mutants of bacteriophage lambda that produce small proheads were found among prophage mutants defective in the major head protein gpE. Measurements of the sedimentation coefficient and molecular weight of the small proheads showed that they have the T = 4 structure composed of 240 molecules of gpE instead of the wild-type T = 7 structure composed(More)