I. K. Malashenkova

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We studied the state of antiviral defense in patients with severe course of herpetic infection of anogenital and labial localization and the frequency of its combination with other herpes virus infections. It was found that severe course of herpetic infection caused by herpes simplex virus occurs against the background of combined secondary immunodeficiency(More)
This review discusses the molecular mechanisms underlying memory consolidation, in particular, the neuroimmune interactions that take place during memory consolidation. Animal models of hippocampus-dependent learning show that cytokines secreted by immune cells are necessary for the neural functions that underlie cognition, such as the long-term(More)
The authors present experimental data on luminol-dependent neutrophil chemiluminescence of blood from patients with drug intolerance. A decrease in intensity of neutrophil and whole blood chemiluminescence was registered in the presence of intolerated drugs. In acute phase of generalized intolerance reaction the chemiluminescence test showed readiness of(More)
Coronary heart disease (CHD) was followed up in 239 patients with rheumatic heart disease. According to the clinical data 40 (16.73%) patients had myocardial infarction (MI), 100 (41.84%) cardiosclerosis (CS), 185 (77.4%) angina pectoris (AP). AP (44.35%) prevailed among the isolated (66.1%) forms of valvular disease, associated AP and CS (23%) among the(More)
The paper presents a discussion on therapeutic results obtained with plasmapheresis treatment in 16 patients with stage II essential hypertension. Thirty-three comparable patients entered a control group of conventional treatment. The test and control patients with stage II hypertension were examined for time-course changes in T- and B-lymphocytes counts,(More)
Objective. To assess the levels of cytokines (IFN-α, IL-2, IL-4, IL-6, IL-8, IL-10, IL-12, IL-15, TNF-α) and IL-1 receptor antagonist (IL-1RA), as well as the levels of vascular endothelial growth factor (VEGF) and its antagonist – soluble receptor (sVEGFR1) – in the serum of patients with Alzheimer’s disease (AD) with early (EOAD) and late (LOAD) onset and(More)