I. J. East

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Three sulfated glycoproteins (ZP-1, ZP-2, and ZP-3) make up the zona pellucida, an extracellular glycocalyx that surrounds mouse oocytes. We have produced five monoclonal antibodies specific to the zona. All five immunoprecipitated ZP-2, and in addition, two of the antibodies immunoprecipitated ZP-3. This suggests the presence of either a common antigenic(More)
Since 2003, highly pathogenic avian influenza (HPAI) due to H5N1 virus has been reported from both domestic poultry and wild birds in 60 countries resulting in the direct death or slaughter of over 250,000,000 birds. The potential exists for HPAI to spread to Australia via migratory shorebirds returning from Asia with the most likely pathway of introduction(More)
The zona pellucida is an extracellular glycocalyx, made of three sulfated glycoproteins, that surrounds mammalian oocytes. Parenterally administered monoclonal antibodies specific for ZP-2, the most abundant zona protein, localize in the zona pellucida. When labeled with iodine-125, these monoclonal antibodies demonstrate a remarkably high(More)
Citation: Bradhurst RA, Roche SE, East IJ, Kwan P and Garner MG (2015) A hybrid modeling approach to simulating foot-and-mouth disease outbreaks in Australian livestock. Foot-and-mouth disease (FMD) is a highly contagious and economically important viral disease of cloven-hoofed animals. Australia's freedom from FMD underpins a valuable trade in live(More)
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