I H Chisholm

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For many years there has been controversy concerning the role of genetic influences in the pathogenesis of age-related macular disease. It is widely believed that the lesions causing visual loss occur in response to age-related changes in Bruch's membrane which are recognised clinically as drusen. In this study the density, size, and confluence of drusen as(More)
OBJECTIVE To determine whether teletherapy with 6-mV photons can reduce visual loss in patients with subfoveal choroidal neovascularization in age-related macular degeneration. DESIGN A multicenter, single-masked, randomized controlled trial of 12 Gy of external beam radiation therapy delivered to the macula of an affected eye vs observation only. (More)
A case is presented of cortical blindness in cranial arteritis. A clinical diagnosis at the time of presentation was based on the integrity of the pupillary light reflex and the absence of visually evoked responses. Pathological examination confirmed bilateral occipital infarction. This report stresses the need for recognizing this presentation of cranial(More)
The following case illustrates how an orbital tumour may mimic a posterior segment mass on funduscopy by virtue of its indentation of the globe. Imaging techniques are shown to be vital in the elucidation of the true pathology. Case report A 30-year-old woman complained of severe throbbing pain in the right orbital region, associated with lacrimation and(More)
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