I-Chuan Li

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In their classic paper which demonstrated the preadaptive origin of phage resistance in bacteria, Luria and Delbriick (1943) proposed the use of the fluctuation test to estimate mutation rates in a bacterial population. Subsequently, a number of investigators have examined this problem from various angles, including formal 1980), all dealing with the(More)
AIM This paper reports a study to compare the quality of life and its correlates for patients undergoing various types of renal replacement therapy. BACKGROUND Patients with end stage renal disease need renal replacement therapy as a substitute for their original kidneys. Different renal replacement therapies have different levels of impact on physical,(More)
The factors that affect reliable estimations of mutation rates (mu) in cultured mammalian somatic cell populations by fluctuation analysis are studied experimentally and statistically. We analyze the differential effect of the final cell population size in each culture (Nt) and the number of parallel cultures (C) on the variation in the rate estimates (mu)(More)
Unequal growth rates between mutant and wild-type cells in a large population constitute a problem for the estimation of mutation rate. Over a period of cell growth, a selective advantage of one cell type over the other might lead to considerable error in the estimation of mutation rate if equal growth rates are assumed. In this study, we propose a formula(More)
Following chemical mutagenesis and multiple-step indirect selection, four clones of Chinese hamster V79 cells were isolated which exhibited auxotrophy for thymidine, deoxycytidine, or deoxyuridine but not for cytidine or uridine. All were resistant to uridine, 3-deazauridine, 5-fluorouridine, thymidine, and cytosine arabinoside at concentrations that were(More)
BACKGROUND Chronic disease patients may undergo long periods of treatment, experience changes in their lifestyle and attitude, as well as have to maintain self-care behaviors to prevent the chronic condition from worsening or to attempt to reduce potential complications. All of the above factors could negatively impact on their quality of life. Empowerment(More)
The purpose of this study was to analyze the work stressors of nurse s aides in long-term care facilities and the factors related to work stressors. One hundred two nurse s aides in long-term care facilities in the Shihlin and Peitou districts of Taipei City were interviewed about work stressors. Of the six types of work stressors, the type patient care(More)
The aim of this study was to illustrate the empowering process for cancer patients through Freire ' s dialogical interviewing. Fifteen interviewees participated in interviews over a period of three months. Five themes of dialogical interviewing for the empowering process were adopted including building rapport, assessing disempowerment issues, facilitating(More)
AIM The purpose of this study was to understand the relationships between organizational empowerment and job satisfaction among nursing assistants at long-term care facilities in Taiwan. BACKGROUND Nursing assistants are the major manpower at long-term care facilities. The responsibilities of nursing assistants are complex and numerous and affect their(More)
The purpose of this study was to analyze correlation between perceptions of control and status of hope in home-based cancer patients. One hundred thirty-seven home-based cancer patients from two hospital-based oncology centers in Taipei were interviewed using a structured questionnaire. The results showed that subjects' perceptions of control and status of(More)