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The curarizing effect of three new aminoglucosidic antibiotics (amikacine, dibékacine and sisomicine) is compared to that the streptomycin. The experiment was carried out on mice. In the first group of experiments, the curare-like action of increasing doses of the antibiotics is studied on a diaphragm-phrenic nerve preparation. In the second group, the(More)
The effects of insulin on contractile activity of isolated heart muscle have been studied in the rat's right ventricle. The method of the isolated organ bath was used with Tyrode as perfusion liquid with constant carbogen bubbling. The addition of insulin to the bath (0.3 U/ml) increased the contractile power. Contractility increase, induced by adrenaline(More)
The effects of carbenicillin and phosphomycin separately or simultaneously, on ADP induced platelet aggregation have been studied in vivo. Platelet aggregation, ADP induced, was inhibited by carbenicillin and phosphomycin. The inhibition was proportional to the concentration of antibiotic. A slight inhibition was observed when platelet rich plasma was(More)
The action of orciprenaline, tolazoline, propanolol and inpea on platelet aggregation induced by ADP epinephrine and norepinephrine was studied in vitro in human platelet-rich plasma. Orciprenaline did not significantly affect aggregation induced by ADP. Tolazoline inhibits the aggregation induced by epinephrine and norepinephrine more intensely than the(More)
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