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In vitro incubation of mouse epidermis homogenate with arachidonJc acid shows the production of small amounts of 8-HETE and 12-HETE by 8and 12-1ipoxygenase, r~tively. To investigate the tissue levels of monohyckoxylated products of linoleic acid (18:2) and arachidonic acid (20:4) in normal, hyperplastic and neoplastic mouse epidermis an assay was developed(More)
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