I. Ali

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A series of 3-[(4-substituted-benzylidene)-amino]-2-phenyl-3H-quinazolin-4-ones (5a-k) were synthesized by reacting 3-amino-2-phenyl-1H-quinazolin-4-one with p-hydroxybenzaldehyde, and then further with various alkyl/benzyl halides or substituted phenacyl bromides. The structures of the compounds were confirmed on the basis of IR, NMR, MS and elemental(More)
A new series of N-(6-chlorobenzothiazol-2-yl)-2-substituted-acetamides (3a–h) and N-(6-chlorobenzothiazol-2-yl)-2-(substituted-benzylidene)hydrazinecarbothioamides (5a–h) were synthesized and characterized by IR, 1H NMR, mass and elemental analysis. In vivo anticonvulsant and acute toxicity screening of all the synthesized compounds showed morpholino (3f)(More)
Several 3-chloro-4-flourophenyl substituted semicarbazones have been synthesized in three steps involving aryl urea and aryl semicarbazide formation. The structures have been confirmed by spectral and elemental analyses. Some selected compounds have been evaluated for anticonvulsant activity by using maximal electroshock seizure (MES) test. The compounds(More)
Bioprosthetic Aortic Valves (BAVs) do not have the serious limitations of mechanical aortic valves in terms of thrombosis. However, the lifetime of BAVs is too short, often requiring repeated surgeries. The lifetime of BAVs might be improved by using computer simulations of the structural behavior of the leaflets. The goal of this study was to develop a(More)
Epilepsy is the most common neurological disorder known, affecting around 1 % of the world’s population, characterized by recurrent seizure attack. A new series of 2-phenyl-3-(3-(substituted-benzylideneamino)-quinazolin-4(3H)-one derivatives (6a–h) was synthesized through condensation of anthranilic acid (1) and benzoyl chloride to give(More)
Context: Smartphone is gaining popularity due to its feasible mobility, computing capacity and efficient energy. Emails, text messaging, navigation and visualizing geo-spatial data through browsers are common features of smartphone. Display of geo-spatial data is collected in computing format and made publically available. Therefore the need of usability(More)
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