I A Kolometsewa

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The injection of 250 microgram/kg SP-analogue (Lys-Phe-Ile-Gly-Leu-MetNH2) is able to restore the reduced or disturbed delta activities and paradoxical sleep periods of the sleeping EEG in chronically stressed rats. Thus it has been proved that Substance P, which we would like to term as an ,,regulatory peptide" (equal to regulide) has a modulating(More)
In the present paper the effects of substance P (SP1-11, Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-MetNH2) and delta sleep inducing peptide (DSIP, Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu) to normalize the deprivation of sleep in chronically stressed rats with hyposomnia were investigated. The results indicated that SP1-11 is more potent than DSIP in rats with(More)
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