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BACKGROUND/AIMS Adefovir (ADV) and lamivudine (LAM) combination therapy (ADV+LAM) has been a useful option for patients with LAM-resistant (LAM-r) chronic hepatitis B (CHB). However, the long-term outcomes of LAM+ADV and 1-mg entecavir (ETV) rescue therapies have still been limited. The aim of this study was to determine the long-term outcomes of these two(More)
We investigate the effect of surface curvature on characteristics of flexible surface plasmon resonance biosensors. For simplified analysis, segmentation-based approximation of curved substrates has been conducted in a range of curvature radius |r| > 225 μm in the parallel and perpendicular light incidence with respect to the surface. The results suggest(More)
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