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Dengue virus infections are a major cause of morbidity in tropical countries. Early detection of dengue hemorrhagic fever (DHF) may help identify individuals that would benefit from intensive therapy. Predictive modeling was performed using 11 laboratory values of 51 individuals (38 DF and 13 DHF) obtained on initial presentation using logistic regression.(More)
OBJECTIVE To examine whether neighborhood-level socioeconomic status is an independent risk factor for health risk behaviors. METHODS Data from the Third National Health and Nutrition Examination Survey were linked with census tracts from the 1990 US Census. Outcome variables included biomarkers for smoking and high dietary fat intake, and self-reported(More)
BACKGROUND Asthma is a heterogeneous clinical disorder. Methods for objective identification of disease subtypes will focus on clinical interventions and help identify causative pathways. Few studies have explored phenotypes at a molecular level. OBJECTIVE We sought to discriminate asthma phenotypes on the basis of cytokine profiles in bronchoalveolar(More)
PURPOSE We examined the influence of nativity and community context (Hispanic neighborhood concentration) on two measures of problem drinking among Mexican-Americans. DESIGN Cross-sectional study. SETTING Texas City Stress and Health Study conducted in Texas City, Texas during 2004-2006. PARTICIPANTS A total of 1435 Mexican-Americans aged 25 years and(More)
Asthmatic patients are currently classified as either severe or non-severe based primarily on their response to glucocorticoids. However, because this classification is based on a post-hoc assessment of treatment response, it does not inform the rational staging of disease or therapy. Recent studies in other diseases suggest that a classification which(More)
BACKGROUND Alzheimer's disease (AD), a progressive, neurodegenerative disorder characterized by memory loss, language deterioration, impairment of visuospatial skills, poor judgment, and indifference, but preserved motor function, is the most common type of dementia, accounting for two thirds or more of all cases of dementia. The identification of(More)
Depression is the most common psychiatric condition among people with multiple sclerosis (MS). A total of 14009 people with MS at admission to a nursing facility were analyzed using the Minimum Data Set and 36% also had depression. This study developed profiles of nursing home residents with MS who also had depression and compared them with other residents(More)
In a previous study, we showed that electroacupuncture (EA) applied to the SI-6 point on the contralateral forelimb produces long-lasting and powerful analgesia in pain caused by ankle sprain in a rat model. To investigate the underlying mechanism of EA analgesia, the present study tested the effects of various antagonists on known endogenous analgesic(More)
Chronic hepatic disease damages the liver, and the resulting wound-healing process leads to liver fibrosis and the subsequent development of cirrhosis. The leading cause of hepatic fibrosis and cirrhosis is infection with hepatitis C virus (HCV), and of the patients with HCV-induced cirrhosis, 2% to 5% develop hepatocellular carcinoma (HCC), with a survival(More)