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Reactive oxygen species (ROS) including superoxide anion and hydrogen peroxide (H(2)O(2)) are thought to be byproducts of aerobic respiration with damaging effects on DNA, protein, and lipid. A growing body of evidence indicates, however, that ROS are involved in the maintenance of redox homeostasis and various cellular signaling pathways. ROS are generated(More)
PURPOSE Although the use of peripherally inserted central catheters (PICCs) has increased in burn patient treatment, little is known about the subjective experiences of these patients with PICCs. These experiences may be similar to those of other patients, particularly cancer patients receiving long term care but it is not clear if this is the case. Burn(More)
Accumulating evidence indicates that protein phosphorylation regulates Nox activity. In this report, we show that serine282 residue of Nox activator 1 (NoxA1) is phosphorylated by Erk in response to EGF resulting in desensitization of Nox1 activity. Specifically, murine NoxA1 is detected as two independent protein bands in SDS PAGE, and the form of protein(More)
PURPOSE Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease, resulting in physical and psychological distress. Little is known about the health of ALS patients in South Korea. The purpose of this study was to assess the degree of functional impairment and depressive symptoms and their interrelationships in Korean ALS patients. METHOD In(More)
The generation of reactive oxygen species (ROS) is required for proper cell signaling, but must be tightly regulated to minimize deleterious oxidizing effects. Activation of the NADPH oxidases (Nox) triggers ROS production and, thus, regulatory mechanisms exist to properly control Nox activity. In this study, we report a novel mechanism in which Nox1(More)
This cross-sectional study explored the level of patient needs and satisfaction in women with day surgery. A consecutive sample of 233 women was recruited from a women's health care center in South Korea. Demographic and disease-specific characteristics, patient needs, and satisfaction were measured. Patient needs were evaluated based on patient-centered(More)
BACKGROUND & AIM Workplace bullying and lateral violence are serious issues affecting the work life of hospital nurses. The purpose of this study was to identify the selected individual and institutional characteristics for workplace bullying and lateral violence using a conceptual framework. METHODS A descriptive survey design was used. A convenience(More)
Photopolymer films containing difunctional methacrylate monomer synthesized from s-triazine were prepared for holographic recording. The holographic recording properties of the films were investigated by changing content of the monomers. The optimized composition showed high diffraction efficiency and low shrinkage. Angular selectivity and grating formation(More)
INTRODUCTION Burn patients experience high levels of pain and anxiety during dressing changes. Relaxation breathing is a simple behavioral intervention to manage pain and anxiety. However, the information about the effects of relaxation breathing on pain and anxiety levels for burn patients during dressing changes is limited. METHODS This study followed a(More)
AIMS AND OBJECTIVES To examine Korean registered nurses' level of perceived knowledge and practice of venous thromboembolism risk assessment as well as prevention, self-efficacy in venous thromboembolism care and actual knowledge of venous thromboembolism. BACKGROUND For hospitalised patients, venous thromboembolism is a preventable clinical disorder.(More)