Hyungtae Kook

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A rare case of spinal epidural granulocytic sarcoma (GS) preceding acute myelogenous leukemia is described. A 10-year-old boy presented with lower leg weakness. The initial diagnosis was a histiocytic lymphoma, and he was treated accordingly. No evidence of bone marrow involvement was found at that time. The correct diagnosis of epidural GS was made(More)
Aspergillus nidulans is one of the several species of Aspergillus with low pathogenicity. The significant infections of A. nidulans in human have rarely been reported, almost exclusively in patients with chronic granulomatous disease (CGD). CGD is a primary immunodeficiency disease which results from the absence of the NADPH oxidase in the phagocytic cells,(More)
It has been known that a diffusive coupling between two limit cycle oscillations typically leads to the in-phase synchronization and also that it is the only stable state in the weak-coupling limit. Recently, however, it has been shown that the coupling of the same nature can result in the distinctive dephased synchronization when the limit cycles are close(More)
Fanconi anemia (FA) is an autosomal recessive disorder of progressive bone marrow failure in patients with congenital malformations. FA is different from acquired aplastic anemia (AA) in terms of the natural course and treatment options. As the frequency of FA is unknown in Korea, we conducted screening tests using DNA clastogenic agents, diepoxybutane(More)
Isolated granulocytic sarcoma (GS) has rarely been reported in a patient who underwent allogeneic bone marrow transplantation (BMT) for chronic myelogenous leukemia (CML). We report here a patient who developed an isolated GS after achieving hematologic and cytogenetic remission by donor lymphocyte infusion for the relapse of CML following BMT. The size of(More)
Pathophysiological implications of the vascular nitric oxide (NO)/cGMP pathway were investigated in various rat models of hypertension. The expression of brain and endothelial constitutive NO synthases (bNOS, ecNOS) was determined by Western blot analysis, and the biochemical activity of soluble and particulate guanylate cyclases (GC) was assessed by the(More)
Synchronization of the coupled neuronal oscillators with multiple connections of different coupling nature is analyzed using the phase-model reduction method. Each coupling connection contributes to the dynamic behavior of the system in a complex nonlinear fashion. In the phase-model scheme, the contribution of the individual connections can be separated in(More)
TRUSTEES AUDITORS EDITORS Theoretical physics, the description of fundamental natural phenomena using mathematics, is something I love deeply and have invested a significant fraction of my life mastering and promoting. Nonetheless it is clear to me that the profession of theoretical physics is in trouble, and that some major rethinking of the business model(More)
Rhythms in the gamma range and the beta range are associated with attention, perception, and cognition. Therefore, the mechanism of how long-distance synchrony between participating sites is achieved becomes one of the important issues of neuroscience. With the help of the phase oscillator model, the stabilities of phase-locked states of beta rhythm are(More)