Hyung-Eun Park

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BACKGROUND AND AIM Both depression and cardiovascular autonomic dysfunctions, such as orthostatic hypotension, supine hypertension, and the absence of normal nocturnal blood pressure (BP) fall ("nondipping"), occur relatively commonly in Parkinson disease (PD); however, the relationship between depression and cardiovascular autonomic abnormalities has not(More)
BACKGROUND Rapid eye movement (REM) sleep behavioral disorder (RBD), orthostatic hypotension (OH), and cardiac sympathetic denervation were commonly observed in PD and are related in both the premotor and motor periods. This study is intended to evaluate if the OH and cardiac sympathetic denervation found in PD are associated with RBD. METHODS Among 94(More)
BACKGROUND AND PURPOSE White matter hyperintensities (WMHs) in the cholinergic pathways are associated with cognitive performance in Alzheimer's disease (AD) and Parkinson disease dementia (PDD). This study aimed to evaluate the relationship between loss of white matter cholinergic pathways and cognitive function in patients with AD, diffuse Lewy body(More)
Dear Sirs, Moyamoya disease is characterized by a progressive narrowing or occlusion of the terminal portion of the internal carotid arteries and the proximal part of the anterior and middle cerebral arteries, with a concomitant development of abnormal collateral vessels.1 Common clinical presentations in childhood are ischemic stroke or transient ischemic(More)
BACKGROUND Impaired renal function and proteinuria have been associated with cognitive impairment and dementia. Chronic kidney disease is considered to be an independent risk factor for Lewy body spectrum disorders (LBD). However, few studies have mentioned an association between proteinuria and cognition in LBD. We investigated the relationship between(More)
Extranigral non-motor signs precede the first motor manifestations of Parkinson’s disease by many years in some patients. The presence of α-synuclein deposition within colon tissues in patients with Parkinson’s disease can aid in identifying early neuropathological changes prior to disease onset. In the present study, we evaluated the roles of non-motor(More)
Spinal myoclonus can be classified into spinal segmental myoclonus and propriospinal myoclonus, in which myoclonic activities spread up and down the spinal cord via propriospinal pathways [1], and can be idiopathic or may be associated with spinal cord disorders. It occurs rarely during drug and toxin exposure, or can be associated with malignancy or(More)
Rabbit syndrome is characterized by fine, rapid, rhythmic movements of the perioral and nasal muscles, without involvement of the tongue. It is commonly associated with long-term neuroleptic medications [1]; in particular, the antipsychotic blockade of dopaminergic neurons would induce a hypercholinergic state that, in turn, might cause rabbit syndrome [2].(More)