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A psychrophilic yeast was isolated from an Arctic pond and its culture supernatant showed ice-binding activity. This isolate, identified as Leucosporidium sp. based on an analysis of the D1/D2 and ITS regions of its ribosomal DNA, produced a secretory ice-binding protein (IBP). Yeast IBP was purified from the culture medium to near homogeneity by the ice(More)
MicroRNA-145 (miR-145) expression is downregulated in several human cancers, but its clinical and functional relevance to ovarian carcinoma has not yet been elucidated. This study addressed the hypothesis that miR-145 serves as a prognostic biomarker and a tumor suppressor that regulates the expression of high-mobility group A2 (HMGA2) oncoprotein in(More)
In Alzheimer's disease (AD), memory impairment is the most prominent feature that afflicts patients and their families. Although reactive astrocytes have been observed around amyloid plaques since the disease was first described, their role in memory impairment has been poorly understood. Here, we show that reactive astrocytes aberrantly and abundantly(More)
Three new members of the cysteine proteinase gene family of Paragonimus westermani have been isolated and classified. Comparisons of the predicted amino acid sequences of PwCP2 (U69121), PwCP4 (U56958), and PwCP5 (U33215) were performed with those of the previously reported PwCP1 (U69120) and PwCP3 (U56865) sequence. The amino acid alignment showed(More)
Psychrobacter spp. have shown characteristics indicating remarkable capabilities at subzero temperatures that identify them as potential model organisms for the study of low-temperature adaptations. Here we present the draft genome sequence of Psychrobacter sp. PAMC 21119, which was isolated from permafrost soil of Antarctica; this information could provide(More)
OBJECTIVE Levonorgestrel releasing intrauterine system (LNG-IUS) has been shown to treat patients with non-atypical & atypical endometrial hyperplasia (EH) successfully in many western studies. Our purpose was to examine the effectiveness of LNG-IUS in the treatment of Korean women with EH. METHODS We conducted a prospective observational study of 12(More)
In this paper, we present a novel method for eye detection based on texture information, referred to as the eye filter. The proposed method is composed of the following four steps: automatic extraction of facial regions using AdaBoost, illumination normalization using local information, estimation of eye candidates by the eye filter based on texture(More)
Manganese superoxide dismutase (leMnSOD) cDNA was cloned from the Antarctic bivalve Laternula elliptica. The full-length cDNA of leMnSOD is 1238 bp in length and contains an open reading frame of 681 bp encoding 226 amino acid residues including a putative mitochondrial targeting peptide of 26 amino acids in the N-terminal region. The calculated molecular(More)
We determined the complete chloroplast DNA sequence of an extremophile plant, Colobanthus quitensis (Antarctic pearlwort), by de novo assembly based on the sequencing results from Illumina MiSeq platform (Illumina Inc., San Diego, CA). The chloroplast genome of C. quitensis (NCBI accession no. KT737383) is a sequence of 151 276 bp long with a typical(More)