Hyun Jung Oh

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Huntington's disease (HD) is a genetic neurodegenerative disorder caused by abnormal expansion of CAG in the huntingtin gene. In R6/2 HD transgenic mice, human adipose-derived stem cells (ASCs) can slow disease progression via secretion of multiple paracrine growth factors. In order to prompt autologous ASCs transplantation in HD, we isolated ASCs from(More)
The establishment and maintenance of proper attachment of kinetochores to microtubules are required to prevent chromosome missegregation and consequent chromosomal instability and tumorigenesis. Although MST1 (mammalian sterile 20-like kinase 1) has been implicated in many aspects of cell cycle regulation and tumor suppression [1], its precise mechanism of(More)
BACKGROUND The Ste-20 family kinase Hippo restricts cell proliferation and promotes apoptosis for proper organ development in Drosophila. In C. elegans, Hippo homolog also regulates longevity. The mammalian Ste20-like protein kinase, Mst1, plays a role in apoptosis induced by various types of apoptotic stress. Mst1 also regulates peripheral naïve T cell(More)
The purpose of this study is to examine whether supportive interactions on social networking sites mediate the influence of SNS use and the number of SNS friends on perceived social support, affect, sense of community, and life satisfaction. Employing momentary sampling, the current study also looked at the relationship between supportive interaction and(More)
In this study we determined whether or not 5-hydroxytryptamine (5-HT) has an effect on the pacemaker activities of interstitial cells of Cajal (ICC) from the mouse small intestine. The actions of 5-HT on pacemaker activities were investigated using a whole-cell patch-clamp technique, intracellular Ca(2+) ([Ca(2+)](i)) analysis, and RT-PCR in ICC.(More)
This study investigates whether and how impression management concerns shape ways people seek social support on social network sites (SNS). The data from a laboratory experiment (N ¼ 176) show that the importance of impression management goals change depending on the publicity of the message, and that the amount of effort in message composition increases as(More)
In the context of healthy snacking, this study examines whether the quality of mental imagery determines the effectiveness of combining the implementation intention (II) intervention with mental imagery. This study further explores whether providing narrative healthy snacking scenarios prior to forming an II enhances people's mental imagery experience when(More)
This study investigates the two facets of the social identity model of deindividuation (SIDE) within the context of online dating and racial stereotyping; visual anonymity and salience of social categorization cues. Experiment 1 (N = 23) employed a 2 (stereotypic attributes) Â 2 (gender) Â 12 (repetition) within-subject design where participants rated(More)
This study explicates mechanisms of media campaign effectiveness in the context of children's physical activity. The authors' model expands the theory of planned behavior by integrating injunctive and descriptive norms into its normative mechanism. Analysis of a 3-wave nationally representative evaluation survey among 1,623 tweens indicates that campaign(More)
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