Hyun Jung Alvarez Oh

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Huntington's disease (HD) is a genetic neurodegenerative disorder caused by abnormal expansion of CAG in the huntingtin gene. In R6/2 HD transgenic mice, human adipose-derived stem cells (ASCs) can slow disease progression via secretion of multiple paracrine growth factors. In order to prompt autologous ASCs transplantation in HD, we isolated ASCs from(More)
In this study we determined whether or not 5-hydroxytryptamine (5-HT) has an effect on the pacemaker activities of interstitial cells of Cajal (ICC) from the mouse small intestine. The actions of 5-HT on pacemaker activities were investigated using a whole-cell patch-clamp technique, intracellular Ca(2+) ([Ca(2+)](i)) analysis, and RT-PCR in ICC.(More)
The purpose of this study is to provide a user-friendly Excel simulation tool for primary care practices to manage appointment schedules which accommodate multiple patient types and stochastic service times for the nurse and provider steps in patient flow. The key features of the Excel tool are: a color-coded schedule of each provider; a Gantt chart as a(More)
Transplantation of patient-derived adipose stem cells in YAC128 Huntington's disease transgenic mice. Abstract Huntington's disease (HD) is a genetic neurodegenerative disorder caused by abnormal expansion of CAG in the huntingtin gene. In R6/2 HD transgenic mice, human adipose-derived stem cells (ASCs) can slow disease progression via secretion of multiple(More)
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