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Reports evaluating the effect of alkalinization of mepivacaine on the onset of regional anesthesia have been controversial. The effect of alkalinization of mepivacaine on the onset of interscalene block has not been reported and is the subject of this study. Forty patients received an interscalene block by elicitation of paresthesia with 25-gauge, blunt(More)
The influence of regional anaesthetic technique on the incidence of lower extremity tourniquet pain was evaluated. We studied 60 patients undergoing orthopaedic procedures of the lower extremity with the use of a pneumatic tourniquet and anticipated inflation of 60 min or longer. Three different anaesthetic techniques were selected by random and draw;(More)
PURPOSE Ankylosing spondylitis is associated with pathophysiology that has important anaesthetic implications. We report a case where the sequelae of ankylosing spondylitis may have been responsible for massive bleeding during emergency spine surgery. CLINICAL FEATURES A 69 yr old man with long standing ankylosing spondylitis sustained a complex fracture(More)
SV40 DNA replication system is a very useful tool to understand the mechanism of replication, which is a tightly regulated process. Many environmental and cellular factors can induce cell cycle arrest or apoptosis by inhibiting DNA replication. In the course of our search for bioactive metabolites from the marine sponges, psammaplin A was found to have some(More)
The effect of pH adjustment of mepivacaine on the incidence of tourniquet pain during axillary brachial plexus anaesthesia was studied. Thirty-nine patients scheduled for hand surgery, during which use of pneumatic tourniquet for longer than 60 min was planned, were randomized into two groups. Both received axillary brachial plexus block with 40 ml, 1.4%(More)
BACKGROUND AND OBJECTIVES Although the majority of elective lumbar spine surgical procedures are performed under general anesthesia, successful use of spinal and epidural anesthesia has been reported. This study was designed to evaluate the influence of baricity on the performance of spinal anesthesia for lumbar spine surgery. METHODS The study was(More)
BACKGROUND AND OBJECTIVES Regional anesthesia can be applied to shoulder surgery with an expected high success rate. To determine the level of patient satisfaction with regional anesthesia, we studied a group of patients who had undergone shoulder surgery more than once, with general anesthesia on one occasion and regional on another. METHODS Twenty-five(More)
STUDY OBJECTIVE To evaluate a large series of elective lumbar spine surgical procedures by a single surgeon whose patients were all offered spinal anesthesia. DESIGN Retrospective chart review. SETTING Tertiary-care teaching hospital. MEASUREMENTS AND MAIN RESULTS The records of all elective lumbar spine procedures between 1984 and 1995 performed by(More)
STUDY OBJECTIVE To evaluate the quality of pain control achieved with continuous local anesthetic infusion via a femoral nerve catheter, and to determine the optimum concentration of bupivacaine necessary to maintain pain control after full surgical anesthesia is established with 0.5% bupivacaine. DESIGN Randomized, prospective study. SETTING Tertiary(More)
STUDY OBJECTIVE To determine the autonomic changes associated with pneumatic tourniquet-induced hypertension as measured by power spectral heart rate analysis (PSHR). DESIGN Prospective study. SETTING Tertiary teaching hospital. PATIENTS 21 healthy-patients scheduled for lower extremity surgery, during which pneumatic tourniquet inflation was expected(More)