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OBJECTIVE The purpose of this study was to prospectively evaluate the usefulness of scoring perfusion defects on perfusion images at dual-energy CT for assessment of the severity of pulmonary embolism. SUBJECTS AND METHODS Thirty patients (13 men, 17 women; mean age, 55 +/- 15 [SD] years; range, 26-81 years) with pulmonary thromboembolism underwent(More)
The purpose of this study is to assess the incidence and type of intimal defects in acute stage of the intramural hematoma (IMH) of the aorta using multi-detector CT (MDCT), and to see whether there was any difference in disease progression according to the presence and types of intimal defects. A retrospective analysis of 37 patients with following(More)
PURPOSE To evaluate the efficacy and safety of transcatheter arterial embolization of the pelvic arteries for the treatment of postpartum hemorrhage (PPH) associated with cesarean section compared with vaginal delivery. MATERIALS AND METHODS A retrospective analysis of 176 patients undergoing transcatheter arterial embolization of the pelvic arteries for(More)
PURPOSE One of the main challenges of lung cancer research is identifying patients at high risk for recurrence after surgical resection. Simple, accurate, and reproducible methods of evaluating individual risks of recurrence are needed. EXPERIMENTAL DESIGN Based on a combined analysis of time-to-recurrence data, censoring information, and microarray data(More)
BACKGROUND Due to the rarity of esophageal gastrointestinal stromal tumors (GISTs), their clinical course and treatment are poorly understood. We have assessed our experience in the diagnosis and management of esophageal GISTs. METHODS We performed a retrospective chart review of patients diagnosed with esophageal GISTs who underwent surgical resection.(More)
Previously, we reported the identification and characterization of a novel cancer/testis antigen gene, CAGE(4), that was expressed in various histological types of tumors, but not in normal tissues, with the exception of the testis. To date, molecular mechanisms for the expression of CAGE have never been studied. In our expression analysis, we found that(More)
An association between inflammatory processes and the pathogenesis of insulin resistance has been increasingly suggested. The IkappaB kinase-beta (IKK-beta)/ nuclear factor-kappaB (NF-kappaB) pathway is a molecular mediator of insulin resistance. S-Adenosyl-L-methionine (SAM) has both antioxidative and anti-inflammatory properties. We investigated the(More)
Adiponectin has been reported to have a wide range of antiatherogenic actions. Two common single nucleotide polymorphisms (SNPs) at the adiponectin locus (45T>G and 276G>T) have been reported to be associated with diabetes and cardiovascular diseases. The aim of this study was to examine the association between common polymorphisms of the adiponectin gene(More)
PURPOSE To prospectively determine the accuracy of portal venous phase helical multi-detector row computed tomography (CT) for bladder lesion evaluation in patients with hematuria by using cystoscopy as the reference standard. MATERIALS AND METHODS The study was approved by the institutional review board for human investigation, and informed consent was(More)
Central thalamus plays a critical role in forebrain arousal and organized behavior. However, network-level mechanisms that link its activity to brain state remain enigmatic. Here, we combined optogenetics, fMRI, electrophysiology, and video-EEG monitoring to characterize the central thalamus-driven global brain networks responsible for switching brain(More)