Hyun Joo An

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The genome sequence of Drosophila melanogaster.

Mark D Adams, Susan E. Celniker, +192 authors J. Craig Venter
Science
2000

The fly Drosophila melanogaster is one of the most intensively studied organisms in biology and serves as a model system for the investigation of many developmental and cellular processes common to… (More)

Simultaneous and extensive site-specific N- and O-glycosylation analysis in protein mixtures.

Charles C Nwosu, Richard R. Seipert, +5 authors Carlito B. Lebrilla
Journal of proteome research
2011

Extensive site-specific glycosylation analysis of individual glycoproteins is difficult due to the nature and complexity of glycosylation in proteins. In protein mixtures, these analyses are even… (More)

Disease-Associated Mutations of TREM2 Alter the Processing of N-Linked Oligosaccharides in the Golgi Apparatus.

Jung Hoon Park, In Jung Ji, +4 authors Seung-Yong Yoon
Traffic
2015

The triggering receptor expressed on myeloid cells 2 (TREM2) is an immune-modulatory receptor involved in phagocytosis and inflammation. Mutations of Q33X, Y38C and T66M cause Nasu-Hakola disease… (More)

Site-specific protein glycosylation analysis with glycan isomer differentiation.

Serenus Hua, Charles C Nwosu, +5 authors Carlito B. Lebrilla
Analytical and bioanalytical chemistry
2012

Glycosylation is one of the most common yet diverse post-translational modifications. Information on glycan heterogeneity and glycosite occupancy is increasingly recognized as crucial to… (More)

Determination of N-glycosylation sites and site heterogeneity in glycoproteins.

Hyun Joo An, Thomas R Peavy, Jerry L. Hedrick, Carlito B. Lebrilla
Analytical chemistry
2003

An approach for the characterization of glycosylation sites and oligosaccharide heterogeneity in glycoproteins based on a combination of nonspecific proteolysis, deglycosylation, and matrix-assisted… (More)

Exposure of iron nanoparticles to Arabidopsis thaliana enhances root elongation by triggering cell wall loosening.

Jae-Hwan Kim, Yongjik Lee, +5 authors Yoon-Seok Chang
Environmental science & technology
2014

In this study, we investigated the effect of nZVI on plant root elongation in Arabidopsis thaliana and showed, for the first time, that nZVI enhanced root elongation by inducing OH radical-induced… (More)

Detecting glycan cancer biomarkers in serum samples using MALDI FT-ICR mass spectrometry data

Donald A. Barkauskas, Hyun Joo An, +7 authors David M. Rocke
Bioinformatics
2009

MOTIVATION The development of better tests to detect cancer in its earliest stages is one of the most sought-after goals in medicine. Especially important are minimally invasive tests that require… (More)

Determination of glycosylation sites and site-specific heterogeneity in glycoproteins.

Hyun Joo An, John W. Froehlich, Carlito B. Lebrilla
Current opinion in chemical biology
2009

Glycosylation is one of the most common post-translational modifications (PTMs) of proteins. At least 50% of human proteins are glycosylated with some estimates being as high as 70%. Glycoprotein… (More)

Evolutionary glycomics: characterization of milk oligosaccharides in primates.

Nannan Tao, Shuai Wu, +6 authors Carlito B. Lebrilla
Journal of proteome research
2011

Free oligosaccharides are abundant components of mammalian milk and have primary roles as prebiotic compounds, in immune defense, and in brain development. A mass spectrometry-based technique is… (More)

Annotation of a serum N-glycan library for rapid identification of structures.

Danielle L Aldredge, Hyun Joo An, Ning Tang, Keith M. Waddell, Carlito B. Lebrilla
Journal of proteome research
2012

Glycosylation is one of the most common post-translational modifications of proteins and has been shown to change with various pathological states including cancer. Global glycan profiling of human… (More)

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