Hyun-Gyu Lee

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TWIST1 is implicated in the process of epithelial mesenchymal transition, metastasis, stemness, and drug resistance in cancer cells, and therefore is a potential target for cancer therapy. In the present study, we found that knockdown of TWIST1 by small interfering RNA (siRNA) enhanced arsenic trioxide (ATO)- and ionizing radiation (IR)-induced cell death(More)
We eliminate similar frames from a wireless capsule endoscopy video of the human intestines to maximize spatial coverage and minimize the redundancy in images. We combine an intensity correction method with a method based an optical flow and features to detect and reduce near-duplicate images acquired during the repetitive backward and forward egomotions(More)
Wireless capsule Endoscopy (WCE) has rapidly shown its wide applications in medical domain last ten years thanks to its noninvasiveness for patients and support for thorough inspection through a patient’s entire digestive system including small intestine. However, one of the main barriers to efficient clinical inspection procedure is that it requires large(More)
In the present study, we found that selective inhibition of histone deacetylase 2 (HDAC2) with small inhibitory RNA (siRNA) induced survivin downregulation in a p53-dependent manner. Interestingly, suberoylanilide hydroxamic acid (SAHA) or knockdown of HDAC2 induced downregulation of Mdm2, a negative regulator of p53, at the protein level. SAHA and/or HDAC2(More)
In this work, a new hybrid nanocatalyst, namely titanium dioxide (TiO2) composite nanowires, encapsulated with graphene (G) and palladium nanoparticles (Pd NPs) (designated as G-Pd@TiO2-CNWs), was prepared. In preparing the nanowires, a combination of electrospinning and hydrothermal approaches was employed. The visible-light-driven photocatalytic(More)
A bag-of-regions (BoR) representation of a video sequence is a spatio-temporal tessellation for use in high-level applications such as video classifications and action recognitions. We obtain a BoR representation of a video sequence by extracting regions that exist in the majority of its frames and largely correspond to a single object. First, the(More)
Use of laser-etched pouches was investigated to develop kimchi packages with gas control functions. According to the degree of laser processing, the headspace pressure, atmospheric composition, and water vapor transmission rate of the kimchi packages were measured to investigate the potential use of laser-etched packages for kimchi. In addition, the pH,(More)
We identify cells in microscopy images with stained nuclei, using the following process: candidate seeds for nuclei are identified as extrema in a Laplacian-of-Gaussian space, and weak candidates are eliminated from clusters obtained by ellipse fitting; a region of interest for each nucleus is then defined by combining local and global thresholding; and(More)
By utilizing a microfluidics approach, we prepared uniformly sized cholesteric liquid crystal (CLC) droplets from MLC-2132 doped with a chiral dopant (S)-4-cyano-4'-(2-methylbutyl)biphenyl (CB15). We studied the helical structures and reflecting color patterns of high- and low-dopant CLC droplets coated with poly(vinyl alcohol) (PVA) and sodium dodecyl(More)