Hyun Guy Kang

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The utility of combined metabolic and volumetric 18F-FDG PET/CT indices for predicting tumour necrosis fractions following neoadjuvant chemotherapy has not been extensively studied in osteosarcoma. Furthermore, little is known of the early PET/CT responses after only one chemotherapy course. Enrolled in the study were 20 children and young adults with(More)
Histologic evaluation of neoadjuvant chemotherapy effect is a well-established prognostic indicator in osteosarcoma and Ewing sarcoma arising in bone. Although tumor necrosis is a primary histologic response for the treatment, secondary degenerative changes following necrosis are frequently shown in those tumors. We reviewed some cases of Ewing sarcoma and(More)
PURPOSE To evaluate whether proton MR spectroscopy (MRS) at 3 T with metabolite quantification is helpful for characterizing musculoskeletal lesions and to reveal whether the concentration of choline is correlated with the pathologic degree of malignancy. MATERIAL AND METHODS Three-tesla MR images and proton MRS data from 27 consecutive patients with(More)
OBJECTIVE Percutaneous stabilization (PS; percutaneous flexible nailing and intramedullary bone cement injection) was performed at lower extremity long bones in patients with multiple bone metastases with short life expectancy to get mechanical stability and local tumor control. We evaluated the usefulness of PS by clinical status, F-18-FDG PET-CT and bone(More)
BACKGROUND We aimed to describe the clinical characteristics and outcomes of unplanned excisions of synovial sarcomas. METHODS In total, 90 patients with synovial sarcomas in the extremities were retrospectively reviewed. Patients were divided into unplanned excision (n = 38) and planned excision (n = 52) groups. The average follow-up period was 6 years.(More)
OBJECTIVE Pathologic or osteoporotic femoral neck fractures usually treated with joint replacement surgery rather than joint-preserving surgery because multiple screw fixation has a high risk for fixation failure and nonunion as well as the need for a postoperative protection period. However, joint-preserving surgery might be preferable in high-risk(More)
While transcription as regulated by histones and their post-translational modifications has been well described, the function of histone variants in this process remains poorly characterized. Potentially important insight into this process pertain to the frequently occurring mutations of H3.3, leading to G34 substitutions in childhood glioblastoma and giant(More)
Tumor samples are required for pathological examinations, and different instruments are generally used to obtain samples of different types of tumors. Among the many methods available for obtaining tumor tissues, gun biopsy is widely used because it is much simpler than incisional biopsy and can collect many more samples than aspiration biopsy. However,(More)
OBJECTIVES Percutaneous cementoplasty (PC) is used for metastatic bone tumor. Bone metastases patients who are unable to avail regular surgery, because of their poor general condition, undergo PC to gain mechanical stability and pain relief. We evaluated the effect of PC using (18)F-FDG PET-CT and investigated the correlation and predictability between(More)