Hyun-Chul Shin

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Gene expression is regulated at the transcriptional and post-transcriptional levels. Therefore, in order to achieve a high level of silencing, which includes minimizing any residual expression of a target gene, suppression at both the transcriptional and post-transcriptional levels is required. In this study, we describe a new method for highly efficient(More)
Protein transduction (PT) is a method for delivering proteins into mammalian cells. PT is accomplished by linking a small peptide tag--called a PT domain (PTD)--to a protein of interest, which generates a functional fusion protein that can penetrate efficiently into mammalian cells. In order to study the functions of a transcription factor (TF) of interest,(More)
In this study, on evaluating the physiological function and mechanism of putrescine, we found that putrescine supplementation (1 mM) increases transcription of the putrescine aminotransferase gene, ygjG. Putrescine-dependent expression was confirmed by measuring β-galactosidase activity and with reverse transcription-polymerase chain reaction. To understand(More)
  • Seung-Ha Han, Hwan-Bae Yu, Hyun-Chul Shin, Jun-Ui Song, Hae-Bum Lee, Jung-Hyuk Choi +5 others
  • 2010
The cell integration density of the NOR flash memory is increasing rapidly. And MLC (multi-level cell) was introduced as a strong method for the evolution of high density and high performance of flash memories in mobile applications [1]. However, MLC technology requires a tight distribution of threshold voltage (Vt) compared to those of single level cell(More)
OBJECTIVE The authors introduce a minimally invasive muscle sparing transmuscular microdiscectomy (MSTM) to treat herniated lumbar disc disease. Its results are compared with conventional subperiosteal microdiscectomy (CSM) to validate the effectiveness. METHODS Muscle sparing transmuscular microdiscectomy, which involves muscle dissection approach using(More)
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