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Outcomes of Early Liver Transplantation for Patients With Severe Alcoholic Hepatitis.
TLDR
In a retrospective analysis of 147 patients who underwent early LT (before 6 months of abstinence) for severe AH, it is found that most patients survive for 1 year (94%) and 3 years (84%), similar to patients receiving liver transplants for other indications. Expand
Predicting Low Risk for Sustained Alcohol Use After Early Liver Transplant for Acute Alcoholic Hepatitis: The Sustained Alcohol Use Post–Liver Transplant Score
TLDR
A prognostic score, the SALT score, using four objective pretransplant variables identifies candidates with AH for early LT who are at low risk for sustained alcohol use posttransplant. Expand
Model to Calculate Harms and Benefits of Early vs Delayed Liver Transplantation for Patients With Alcohol-Associated Hepatitis.
TLDR
In a modeling study of assumed carefully selected patients with severe AH, early vs delayed liver transplantation (6 months of abstinence from alcohol before transplantation) increased survival times of patients, regardless of estimated risk of sustained alcohol use after transplantation. Expand
Hepatitis E viral infection in solid organ transplant patients
TLDR
Infection with HEV is a rare but significant infection in organ transplant recipients, being recognized both in developing and developed nations as a cause of cirrhosis, and, in some cases, of fulminant hepatic failure. Expand
Acute Hepatocellular Drug-Induced Liver Injury From Bupropion and Doxycycline
TLDR
A 29-year-old African American man who presented with jaundice and malaise after starting bupropion and doxycycline was found to have acute hepatocellular drug-induced liver injury with autoimmune features, and made a complete recovery with prednisone. Expand
Underestimation of Liver Transplantation for Alcoholic Hepatitis in the National Transplant Database
TLDR
In a large cohort of LT recipients with AH, only 35% were documented as such in UNOS, and increased education and awareness for those performing UNOS data entry, the establishment of specific criteria to define AH in the UNOS database, and the ability to document dates of alcohol use would allow future research to be more informative. Expand
Checkpoint Inhibitor–Induced Rejection of a Liver Allograft: A Combination of Acute T Cell–Mediated and Antibody‐Mediated Rejection
TLDR
Safety of Pembrolizumab or Nivolumab in liver transplant recipients is unfamiliar and previous case reports have documented the development of allograft rejection in patients receiving these agents. Expand
Skin cancer and dermatoses in a majority Hispanic population of solid organ transplant recipients.
Cytomegalovirus in liver transplant recipients
TLDR
Until that time, aggressive monitoring of post-transplant patients for signs and symptoms of CMV infection is the best strategy to prevent solid-organ loss and death. Expand
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