Hyon Lee

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Background and aim Alveolar fluid clearance is impaired by inducible nitric oxide synthase (iNOS)/nitric oxide (NO)-dependent mechanisms in acute lung injury (ALI)/acute respiratory distress syndrome (ARDS). The activation of the stress protein response (SPR) in alveolar macrophages on iNOS-dependent NO production in response to interferon g (IFNg), a major(More)
The aim of this study was to investigate how the interrelationships between low-frequency oscillations (LFOs) in the cerebral and systemic cardiovascular hemodynamic systems change with aging and systemic hemodynamic perturbation. Seventeen young adult (28.4±3.5years) and seventeen elderly subjects (69.4±8.7years) underwent continuous measurements of(More)
BACKGROUND Chronic renal insufficiency, diagnosed using creatinine based estimated glomerular filtration rate (GFR) or microalbumiuria, has been associated with the presence of cerebral microbleeds (CMBs). Cystatin C has been shown to be a more sensitive renal indicator than conventional renal markers. Under the assumption that similar pathologic mechanisms(More)
PURPOSE Phase contrast magnetic resonance angiography (PC MRA) is an important, non-invasive method for obtaining quantitative information on blood flow. The purpose of the present study was to investigate the dynamic cerebral arterial response in humans to visual stimulation by quantitative velocity analysis using PC MRA. METHODS Functional PC MRA (fPCA)(More)
BACKGROUND Insulin, a pleotrophic hormone, has diverse effects in the body. Recent work has highlighted the important role of insulin's action in the nervous system on glucose and energy homeostasis, memory, and mood. SCOPE OF REVIEW Here we review experimental and clinical work that has broadened the understanding of insulin's diverse functions in the(More)
While communicable diseases still pose a serious health threat in developing countries, previously neglected health issues caused by non-communicable diseases such as stroke are rapidly becoming a major burden to these countries. In this review we will discuss the features and current status of stroke in low- and middle-income countries (LMICs). Overall the(More)
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