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BACKGROUND Ablative carbon dioxide fractional laser systems (CO(2) FS) have been effectively used to improve the appearance of scarring after surgical procedures, but an optimal treatment time has not been established. OBJECTIVE To evaluate the efficacy and safety of CO(2) FS in early postoperative thyroidectomy scars. METHODS Twenty-three Korean women(More)
BACKGROUND Melasma is difficult to treat and often recalcitrant to various treatments such as topical preparations and lasers. OBJECTIVES To evaluate the efficacy and safety of the 1064-nm Q-switched Nd:YAG laser in Asian patients with melasma. METHODS Twenty-three Korean patients (skin types III-V) with melasma were treated with the 1064-nm Q-switched(More)
BACKGROUND Melanoma in dark-skinned individuals often develops in an acral lentiginous fashion on the foot. After wide excision, substantial defects usually develop and they may endure insufficient vascular flow. In addition, the final scar must withstand the mechanical stress of daily walking. Various repair methods are used to repair these defects, but(More)
BACKGROUND Matrix metalloproteinase (MMP), tissue inhibitor of metalloproteinase (TIMP), and membrane-type 1 matrix metalloproteinase (MT1-MMP) are thought to be involved in the destruction of basement membrane and stromal invasion by cancer cells. OBJECTIVE The aim of this study was to identify and compare MMP and TIMP expression in internal malignancies(More)
BACKGROUND A number of reports have been published regarding the use of imiquimod for the treatment of melanoma in situ and metastatic melanoma. Essential steps in the process of melanoma invasion and metastasis include degradation of basement membranes and remodeling of the extracellular matrix by proteolytic enzymes, including matrix metalloproteinases(More)
BACKGROUND Phytoclear-EL1, an extract from Euphorbia lathyris seeds, has a whitening effect due to inhibition of tyrosinase activity. OBJECTIVE The purpose of this study was to investigate the inhibitory effect of phytoclear-EL1 on melanogenesis. METHODS Cultured B-16 melanoma cells and 30 human volunteers were used for in vitro and in vivo studies,(More)
Post-steroid panniculitis is known to be very rare and most of the reported cases have been in children after corticosteroid therapy. We present a case of post-steroid panniculitis occurring in a 60-year-old man after massive, long-term administration of corticosteroids for acute exacerbation of chronic obstructive pulmonary disease (COPD).(More)