Hyo-Jeong Lee

Learn More
The functional status of central neural pathways, in particular their susceptibility to plasticity and functional reorganization, may influence speech performance of deaf cochlear implant users. In this paper, we sought to determine how brain metabolic activity measured before implantation relates to cochlear implantation outcome, that is, speech(More)
PURPOSE Cochlear implantation is an effective technique for restoring hearing in the profoundly deaf. Although cochlear implants are a therapeutical success, huge performance variability in speech comprehension is observed after implantation. The reason for this remains incompletely understood after 20 years of clinical practice and basic research. Which(More)
It is commonly held that losing one sense provokes cross-modal takeover of deprived cortical areas, and therefore results in a benefit for the remaining modalities. Using functional magnetic resonance imaging (fMRI), we assessed the impact of acquired deafness on the brain network related to speechreading and teased apart cortical areas with responses(More)
Methylselenol has been implicated as an active anticancer selenium (Se) metabolite. However, its in vivo efficacy against prostate cancer (PCa) has yet to be established. Here, we evaluated the growth inhibitory effects of two presumed methylselenol precursors methylseleninic acid (MSeA) and Se-methylselenocysteine (MSeC) in comparison with selenomethionine(More)
Post-lingual deafness induces a decline in the ability to process phonological sounds or evoke phonological representations. This decline is paralleled with abnormally high neural activity in the right posterior superior temporal gyrus/supramarginal gyrus (PSTG/SMG). As this neural plasticity negatively relates to cochlear implantation (CI) success, it(More)
Androgen and androgen receptor (AR)-mediated signaling are crucial for the development of prostate cancer. Identification of novel and naturally occurring phytochemicals that target androgen and AR signaling from Oriental medicinal herbs holds exciting promises for the chemoprevention of this disease. In this article, we report the discovery of strong and(More)
Angiogenesis is associated with growth, invasion, and metastasis of human solid tumors. Aberrant activation of endothelial cells and induction of microvascular permeability by a vascular endothelial growth factor (VEGF) receptor-2 (VEGFR-2) signaling pathway is observed in pathological angiogenesis including tumor, wound healing, arthritis, psoriasis,(More)
Compound K (CK; 20-O-beta-D-glucopyranosyl-20(S)-protopanaxadiol), an active ginseng saponin metabolite, exerts anticancer activity via apoptosis induction in various cancers. In the present study, we investigated the anti-angiogenic activity of CK and its molecular mechanisms in human umbilical vein endothelial cells (HUVECs). Angiogenesis was induced in(More)
This study explores the characteristics of bacterial and fungal communities of total suspended particles (TSP) in the atmosphere by using various molecular methods. TSP samples were collected on a glass fiber filter at an urban location in the middle of the Korean Peninsula (Seoul) between middle autumn and early winter in 2007. From the aerosol samples,(More)
OBJECTIVES The purpose of this study was to evaluate the responses of peri-implant tissue in the presence of keratinized mucosa. STUDY DESIGN A total of 276 implants were placed in 100 patients. From the time of implant placement, the average follow-up observation period was 13 months. The width of keratinized mucosa was compared and evaluated through the(More)