Hylke Buisman

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A new generation of active 3D range sensors, such as time-of-flight cameras, enables recording of full-frame depth maps at video frame rate. Unfortunately, the captured data are typically starkly contaminated by noise and the sensors feature only a rather limited image resolution. We therefore present a pipeline to enhance the quality and increase the(More)
Extracellular ATP in its tetra-anionic form (ATP4-) induces ion fluxes and membrane depolarization in the mouse macrophage-like cell line J774.2 and in resident mouse macrophages. We analyzed the effects of extracellular ATP4- by both patch-clamp and intracellular microelectrode techniques. Whole-cell patch-configuration membrane potential measurements on(More)
Building qualitative models is still a difficult and lengthy endeavour for domain experts. This paper discusses progress towards an automated modelling algorithm that learns Garp3 models based on a full qualitative description of the system’s behaviour. In contrast with other approaches (Bridewell et al. 2008; Bratko and Šuc 2004), our algorithm attempts to(More)
Patch-clamp measurements were made on osteoblast-like cells isolated from embryonic chick calvaria. Cell-attachedpatch measurements revealed two types of high conductance (100–250 pS) channels, which rapidly activated upon 50–100 mV depolarization. One type showed sustained and the other transient activation over a 10-sec period of depolarization. The(More)
Introduction Osteoclasts (OC) are large (mean C m 50 pF), multinucleated, bone resorbing cells which are formed by fusion of OC progenitor cells. The latter are derived from hemopoietic stem cells and may be identical to macrophage progenitors (Nijweide et al. 1986). OC resorb bone by secreting protons on to the bone surface (Baron et al. 1985). Since this(More)
A novel design for a pipette holder for use in patch-clamp experiments is presented. The holder is designed for use in patch-clamp amplifiers equipped with female BNC-type connectors on the headstage. In this design the glass micropipette cannot contact the Ag/AgCl electrode, thus avoiding deterioration and subsequent offset voltages and baseline current(More)
This paper presents a weakly supervised method that decomposes potentially compositional topics (Swiss passport) into zero or more constituent topics (Switzerland, Passport), where all topics are entries in a knowledge repository. The method increases the connectivity of the knowledge repository and, more importantly, identifies the constituent topics whose(More)
In distributed approaches to multiagent resource allocation, the agents belonging to a society negotiate deals in small groups at a local level, driven only by their own rational interests. We can then observe and study the effects such negotiation has at the societal level, for instance in terms of the economic efficiency of the emerging allocations. Such(More)