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Ectopic Expression of a Cecropin Transgene in the Human Malaria Vector Mosquito Anopheles gambiae (Diptera: Culicidae): Effects on Susceptibility to Plasmodium
A unique pattern of expression of cecropin A in Anopheles gambiae was created such that cecA was expressed beginning 24 h after a blood meal in the posterior midgut, resulting in a 60% reduction in the number of oocysts in transgenic mosquitoes compared with nontransgenic mosquitoes. Expand
Antimicrobial peptides under clinical investigation
Overuse of conventional antibiotics as well as the slow pace of new antibiotic drug development leads to antimicrobial resistance (AMR). Because infections with multi‐drug resistant (MDR) pathogensExpand
Phylogenetic relationships of Acheilognathidae (Cypriniformes: Cyprinoidea) as revealed from evidence of both nuclear and mitochondrial gene sequence variation: evidence for necessary taxonomic
This study provides the most comprehensive phylogenetic reconstruction of species relationships of the Acheilognathidae based on partitioned maximum likelihood and Bayesian methods using DNA sequence variation of nuclear and mitochondrial genes on 41 species, several subspecies and three undescribed species. Expand
Eye primordium transplantation in Xenopus embryo
Cells transplanted from stage-23/24 Xenopus borealis are consistent with the hypothesis that these cells belong to both glia and neuron types, and migrate freely through the cellular bridge to several CNS regions. Expand
Cell migration from the transplanted olfactory placode in Xenopus
Along the nerve originating from the transplanted organ, a stream of cells with the characteristics of the donor penetrated the host's CNS and became incorporated into it, suggesting some of the migrating cells are neurons. Expand
A machine learning based method for the prediction of G protein-coupled receptor-binding PDZ domain proteins
In order to characterize the network of interactions between amino acid residues that contribute to the stability of the PDZ domain-ligand complex and to encode the complex into a feature vector, amino acid contact matrices and physicochemical distance matrix were constructed and adopted. Expand
DNA barcode-based molecular identification system for fish species
A web-based molecular identification system for fish (MISF) is successfully developed using a profile hidden Markov model, which facilitates efficient and reliable species identification, overcoming the limitations of conventional taxonomic approaches. Expand
DNA chip for species identification of Korean freshwater fish: A case study
The COI gene was quite suitable for designing species-specific oligonucleotide probes and a DNA chip arrayed with these probes showed high resolution for species identification, and can be further developed for different purposes by optimal species selection in biodiversity studies and environmental monitoring. Expand
Korea Barcode of Life Database System (KBOL)
A large-scale database system that holds a collection of 5531 barcode sequences from 2429 Korean species is constructed that provides an effective molecular tool for species identification. Expand
A New Record of Betaeus gelasinifer Nomura and Komai (Decapoda: Caridea: Alpheidae) from Korea
An alpheid shrimp Betaeus gelasinifer Nomura and Komai, 2000 new to Korean waters is described and illustrated based on two specimens collected from Changseun and Ulleungdo Island, Korea. This is theExpand